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42867

Solfato di destrano

Mr ~40,000

Sinonimo/i:

Destrano solfato di sodio DSS

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A voi/SKUDisponibilitàPrezzo
5 g
Per informazioni sulla disponibilità, contatta il Servizio Clienti.
116,00 €
25 g
Per informazioni sulla disponibilità, contatta il Servizio Clienti.
438,00 €
100 g
Per informazioni sulla disponibilità, contatta il Servizio Clienti.
1.320,00 €

Informazioni su questo articolo

NACRES:
NA.25
UNSPSC Code:
12352201

116,00 €


Per informazioni sulla disponibilità, contatta il Servizio Clienti.

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form

powder

Quality Segment

mol wt

Mr ~40,000

technique(s)

tissue culture: suitable

loss

≤10% loss on drying

color

white to off-white

useful pH range

6.0-8 (10 g/L)

mp

(Decomposes on heating.)

solubility

water: soluble

suitability

suitable for component for culture media

storage temp.

room temp

General description

Il destrano è un polimero dell′anidroglucosio. È composto al 95% circa da legami alpha-D-(166). I legami rimanenti (163) sono responsabili della ramificazione del destrano.

Application

Il destrano solfato è usato abitualmente per la precipitazione selettiva delle lipoproteine, l′ibridazione con sonde del DNA immobilizzato su membrana, il rilascio di DNA da complessi DNA-istone e l′inibizione del legame dell′RNA con i ribosomi.

Biochem/physiol Actions

Il trattamento con destrano sodio solfato attiva lo sviluppo della colite nei topi e nei ratti legandosi agli acidi grassi a catena media presenti nel colon e inducendo l′infiammazione. [1]

Other Notes

Per acquisire un quadro completo della nostra ampia selezione di destrani disponibili per la vostra ricerca, vi invitiamo a consultare la nostra pagina dedicata ai Carboidrati.

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5122775027RES2029D-A7
technique(s)

tissue culture: suitable

technique(s)

-

technique(s)

-

technique(s)

cell culture | mammalian: suitable

solubility

water: soluble

solubility

H2O: 100 mg/mL, clear, colorless to faintly greenish-yellow

solubility

H2O: 100 mg/mL, clear, colorless to faintly greenish-yellow

solubility

-

Quality Level

100

Quality Level

100

Quality Level

-

Quality Level

300

suitability

suitable for component for culture media

suitability

-

suitability

-

suitability

suitable for manufacturing use

form

powder

form

powder

form

powder

form

powder

storage temp.

room temp

storage temp.

room temp

storage temp.

room temp

storage temp.

-


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Classe di stoccaggio

11 - Combustible Solids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable



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Certificati d'analisi (COA)

Lot/Batch Number

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Domande

1–4 di 4 domande  
  1. How can I determine the shelf life / expiration / retest date of this product?

    1 risposta
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/418/501/product-dating-information-06-25-mk.pdf

      Utile?

  2. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 risposta
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

      Utile?

  3. Does DDS (Dextran Sodium Sulfate) come in a USP grade for a animal studies?

    1 risposta
    1. Unfortunately, there is no pharmaceutical grade Dextran Sodium Sulfate available at this time. This product is not tested for use in animal models. It would be up to the researcher to determine suitability.

      Utile?

  4. Hello! I want to know if you can autoclave water with 4% of dextran sulfate sodium (DSS) without decomposing the DSS.

    1 risposta
    1. The solubility of dextran sulfates is tested at 100 mg/mL in water. Clear solutions are obtained. Buffered aqueous dextran sulfate solutions can be sterilized by autoclaving at 110-115 °C for 30 to 45 minutes. Dextran can be hydrolyzed by strong acids at high temperatures. Dextran sulfate has a higher affinity for calcium ions than for sodium ions. The calcium salt of dextran sulfate is insoluble. The free acid (hydrogen) form of dextran sulfate is extremely acidic and autohydrolyzes rapidly in solution and as a powder.

      More information can be found here: https://www.sigmaaldrich.com/technical-documents/protocol/protein-biology/protein-pulldown/dextran-sulfate

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