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385M-1

Sigma-Aldrich

SALL4 (6E3) Mouse Monoclonal Antibody

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About This Item

Codice UNSPSC:
12352203
NACRES:
NA.41

Origine biologica

mouse

Livello qualitativo

100
500

Coniugato

unconjugated

Forma dell’anticorpo

culture supernatant

Tipo di anticorpo

primary antibodies

Clone

6E3, monoclonal

Descrizione

For In Vitro Diagnostic Use in Select Regions (See Chart)

Forma fisica

buffered aqueous solution

Reattività contro le specie

human

Confezionamento

vial of 0.1 mL concentrate (385M-14)
vial of 0.5 mL concentrate (385M-15)
bottle of 1.0 mL predilute (385M-17)
vial of 1.0 mL concentrate (385M-16)
bottle of 7.0 mL predilute (385M-18)

Produttore/marchio commerciale

Cell Marque

tecniche

immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:25-1:100

Isotipo

IgG1

Controllo

dysgerminoma, seminoma

Condizioni di spedizione

wet ice

Temperatura di conservazione

2-8°C

Visualizzazione

nuclear

Informazioni sul gene

human ... SALL4(57167)

Descrizione generale

Sal-like protein 4 (SALL4) is a zinc-finger transcription factor that serves as a master regulator of embryonic pluripotency and is involved in processes associated with stem cell activities. SALL4 expression in germ cells makes it a useful marker for germ cell tumors such as seminoma, embryonal carcinoma, yolk sac tumors, and teratomas. SALL4 expression is also seen in the spermatogonia of the normal testis.

Qualità


IVD

IVD

IVD

RUO

Linkage

SALL4 Positive Control Slides, Product No. 385S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).

Stato fisico

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide

Nota sulla preparazione

Download the IFU specific to your product lot and formatNote: This requires a keycode which can be found on your packaging or product label.

Altre note

For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com

Note legali

Cell Marque is a trademark of Merck KGaA, Darmstadt, Germany

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Certificati d'analisi (COA)

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Dengfeng Cao et al.
The American journal of surgical pathology, 33(7), 1065-1077 (2009-04-25)
The diagnosis of testicular germ cell tumors (GCTs) sometimes can be challenging without ancillary markers. Here we performed an immunohistochemical study of a novel stem cell marker SALL4 in a large series of 110 primary testicular GCTs (65 pure and
Wei Cui et al.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc, 19(12), 1585-1592 (2006-09-26)
SALL4, a newly identified zinc-finger transcriptional factor important for embryonic development, is mapped to chromosome 20q13. Previously, we reported that SALL4 was constitutively expressed in acute myeloid leukemia and SALL4 transgenic mice developed acute myeloid leukemia. In this study, we
Dengfeng Cao et al.
The American journal of surgical pathology, 33(6), 894-904 (2009-03-20)
Ovarian primitive germ cell tumors (GCTs) are uncommon tumors and sometimes pose diagnostic challenges. Among them, yolk sac tumor (YST) poses the greatest diagnostic difficulty and can be mistaken for clear cell carcinoma (CCC). Current immunohistochemical markers such as alpha-fetoprotein

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