Passa al contenuto
Merck
Tutte le immagini(1)

Documenti

338R-2

Sigma-Aldrich

TdT (EP266) Rabbit Monoclonal Primary Antibody

Sinonimo/i:

Terminal Deoxynucleotidyl Transferase

Autenticatiper visualizzare i prezzi riservati alla tua organizzazione & contrattuali


About This Item

Codice UNSPSC:
12352203

Origine biologica

rabbit

Livello qualitativo

100
500

Coniugato

unconjugated

Forma dell’anticorpo

culture supernatant

Tipo di anticorpo

primary antibodies

Clone

EP266, monoclonal

Descrizione

For In Vitro Diagnostic Use in Select Regions

Forma fisica

buffered aqueous solution

Reattività contro le specie

human

Confezionamento

vial of 0.1 mL concentrate (338R-24)
vial of 0.1 mL concentrate Research Use Only (338R-24-RUO)
vial of 0.5 mL concentrate (338R-25)
vial of 1.0 mL concentrate (338R-26)
vial of 1.0 mL concentrate Research Use Only (338R-26-RUO)
vial of 1.0 mL pre-dilute Research Use Only (338R-27-RUO)
vial of 1.0 mL pre-dilute ready-to-use (338R-27)
vial of 7.0 mL pre-dilute ready-to-use (338R-28)
vial of 7.0 mL pre-dilute ready-to-use Research Use Only (338R-28-RUO)

Produttore/marchio commerciale

Cell Marque

tecniche

immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:50-1:200 (concentrated)

Isotipo

IgG

Controllo

thymus

Condizioni di spedizione

wet ice

Temperatura di conservazione

2-8°C

Visualizzazione

nuclear

Informazioni sul gene

human ... DNTT(1791)

Descrizione generale

TdT (terminal deoxynucleotidyl transferase) is a template-independent DNA polymerase that adds nucleotides randomly to single-stranded DNA. This randomization plays a role in acquired immunity by increasing antigen receptor diversity and aiding in the generation of immunoglobulins and T cell antigen receptors. TdT expression is characteristic of lymphoid progenitor cells in thymus and tonsils. Anti-TdT is a useful marker for lymphoblastic lymphomas and has been observed in some cases of acute myeloid leukemia.

Qualità


IVD

IVD

IVD

RUO

Linkage

TdT Positive Control Slides, Product No. 338S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections)

Stato fisico

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide.

Nota sulla preparazione

Download the IFU specific to your product lot and format
Note: This requires a keycode which can be found on your packaging or product label.

Download the latest released IFU
Note: This IFU may not apply to your specific product lot.

Altre note

For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com

Note legali

Cell Marque is a trademark of Merck KGaA, Darmstadt, Germany

Not finding the right product?  

Try our Motore di ricerca dei prodotti.

Codice della classe di stoccaggio

12 - Non Combustible Liquids

Classe di pericolosità dell'acqua (WGK)

WGK 2

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable


Certificati d'analisi (COA)

Cerca il Certificati d'analisi (COA) digitando il numero di lotto/batch corrispondente. I numeri di lotto o di batch sono stampati sull'etichetta dei prodotti dopo la parola ‘Lotto’ o ‘Batch’.

Possiedi già questo prodotto?

I documenti relativi ai prodotti acquistati recentemente sono disponibili nell’Archivio dei documenti.

Visita l’Archivio dei documenti

Edward A Motea et al.
Biochimica et biophysica acta, 1804(5), 1151-1166 (2009-07-15)
Nearly every DNA polymerase characterized to date exclusively catalyzes the incorporation of mononucleotides into a growing primer using a DNA or RNA template as a guide to direct each incorporation event. There is, however, one unique DNA polymerase designated terminal
James A Strauchen et al.
International journal of surgical pathology, 11(1), 21-24 (2003-02-25)
To investigate the occurrence of lymphoid progenitor cells in human tonsils, we studied tonsils from children and adults by immunohistochemistry by using a panel of antibodies to antigens associated with lymphoid progenitor cells, including terminal deoxynucleotidyl transferase (TdT), CD10 (CALLA)
J Suzumiya et al.
The Journal of pathology, 182(1), 86-91 (1997-05-01)
Terminal deoxynucleotidyl transferase (TdT) is a DNA polymerase located in the cell nucleus which catalyses the polymerization of deoxynucleotides at the 3'hydroxyl ends of oligo- or polydeoxynucleotide initiators without a template. TdT is known as a useful marker for the
D A Arber et al.
American journal of clinical pathology, 106(4), 462-468 (1996-10-01)
The immunohistochemical evaluation of acute leukemia specimens has been limited in the past due of the inability to detect many lineage-related antigens in paraffin sections. With the improvement in immunohistochemical methods as well as the introduction of new antibodies, these

Il team dei nostri ricercatori vanta grande esperienza in tutte le aree della ricerca quali Life Science, scienza dei materiali, sintesi chimica, cromatografia, discipline analitiche, ecc..

Contatta l'Assistenza Tecnica.