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04276

Sigma-Aldrich

Fosfato di sodio

puriss., meets analytical specification of Ph. Eur., BP, USP, FCC, E 339, anhydrous, 98-100.5% (calc. to the dried substance)

Sinonimo/i:

sec-fosfato di sodio, Idrogenofosfato di sodio, Sodio fosfato bibasico

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About This Item

Formula condensata:
Na2HPO4
Numero CAS:
7558-79-4
Peso molecolare:
141.96
Numero CE:
231-448-7
Numero MDL:
MFCD00003496
Codice UNSPSC:
12161700
eCl@ss:
38070211
ID PubChem:
329747909
NACRES:
NA.25

agenzia

meets analytical specifications of BP
meets analytical specifications of Ph. Eur.
meets analytical specifications of USP

Grado

puriss.

Saggio

98-100.5% (calc. to the dried substance)

Forma fisica

powder

Qualità

meets analytical specification of Ph. Eur., BP, USP, FCC, E 339

Impurezze

reducing matter, complies
 residual solvents, complies
≤0.001% heavy metals (as Pb)
≤0.002% ammonium (NH4)
≤0.2% water-insoluble matter
≤1% NaH2PO4 (calc. to dried subst.)
≤2.0% pyrophosphate (as Na4P2O7)

Perdita

≤1% loss on drying, 105°C, 4h
≤1% loss on drying, 130 °C

pH

8.4-9.6 (20 °C, 1%)

pKa (25 °C)

(1) 2.15, (2) 6.82, (3) 12.38 (phosphoric acid)

Solubilità

H2O: soluble 8 parts
H2O: very soluble (Hot)
alcohol: insoluble

Anioni in tracce

chloride (Cl-): ≤50 mg/kg
fluoride (F-): ≤10 mg/kg
sulfate (SO42-): ≤200 mg/kg

Cationi in tracce

As: ≤2 mg/kg
Cd: ≤1 mg/kg
Cu: ≤10 mg/kg
Fe: ≤20 mg/kg
Hg: ≤1 mg/kg
Pb: ≤4 mg/kg
Zn: ≤10 mg/kg

Compatibilità

complies for appearance of solution

Stringa SMILE

[Na+].[Na+].[H]OP([O-])([O-])=O

InChI

1S/2Na.H3O4P/c;;1-5(2,3)4/h;;(H3,1,2,3,4)/q2*+1;/p-2
BNIILDVGGAEEIG-UHFFFAOYSA-L

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Applicazioni

Sodium phosphate dibasic has been used for preparing phosphate buffer which in turn is utilized in X-gal staining.

Azioni biochim/fisiol

Sodium phosphate dibasic is an important component of running buffer of denaturing gel electrophoresis. It induces glomerular calcification as well as other nephrotic syndrome in Sprague-Dawley rats.

Codice della classe di stoccaggio

13 - Non Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 1

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Certificati d'analisi (COA)

Cerca il Certificati d'analisi (COA) digitando il numero di lotto/batch corrispondente. I numeri di lotto o di batch sono stampati sull'etichetta dei prodotti dopo la parola ‘Lotto’ o ‘Batch’.

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Toxicologic pathology, 32(4), 408-412 (2004-06-19)
To elucidate the nephrotoxicity of phosphate, dibasic sodium phosphate solution was given to Sprague-Dawley rats by daily bolus intravenous administration at concentrations of 0, 1, 25, 250, or 360 mM (0, 1, 28, 284, or 408 mg/kg Na2HPO4) for 14
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Sprague-Dawley rats received once daily tail-vein injections of 360 mM dibasic sodium phosphate solution at 8 mL/kg for fourteen or twenty-eight days. Clinical examination revealed persistent proteinuria from three days after the first dosing and thereafter severe proteinuria from eight
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