D2255000

Dinoprost trometamol

European Pharmacopoeia (EP) Reference Standard

• Sinonimo/i: Prostaglandin F_2α tris salt, (5Z,9α,11α,13E,15S)-9,11,15-Trihydroxyprosta-5,13-dienoic acid tris salt, PGF_2α−Tris
• Formula empirica (notazione di Hill): C₂₀H₃₄O₅ · C₄H₁₁NO₃
• Numero CAS: 38562-01-5
• Peso molecolare: 475.62
• Beilstein: 4087514
• Numero MDL: MFCD00077863
• Codice UNSPSC: 41116107
• ID PubChem: 329798735
• NACRES: NA.24

Proprietà

• Grado: pharmaceutical primary standard
• Famiglia di API: dinoprost
• Produttore/marchio commerciale: EDQM
• applicazioni: pharmaceutical (small molecule)
• Formato: neat
• Stringa SMILE: NC(CO)(CO)CO.[H][C@]1(C\C=C/CCCC(O)=O)[C@@H](O)C[C@@H](O)[C@]1([H])\C=C\[C@@H](O)CCCCC
• InChI: 1S/C20H34O5.C4H11NO3/c1-2-3-6-9-15(21)12-13-17-16(18(22)14-19(17)23)10-7-4-5-8-11-20(24)25;5-4(1-6,2-7)3-8/h4,7,12-13,15-19,21-23H,2-3,5-6,8-11,14H2,1H3,(H,24,25);6-8H,1-3,5H2/b7-4-,13-12+;/t15-,16+,17+,18-,19+;/m0./s1; IYGXEHDCSOYNKY-RZHHZEQLSA-N
• Informazioni sul gene: human ... PTGFR(5737)

Descrizione

Descrizione generale

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the Issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Applicazioni

Dinoprost trometamol EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Azioni biochim/fisiol

Luteolytic prostaglandin that induces parturition. Potent vasoconstrictor of pulmonary, coronary, and cerebral arteriole beds. A positive feedback loop between endometrial PG F_2α and luteal oxytocin is responsible for completion of luteolysis.

Luteolytic prostaglandin that induces parturition. Potent vasoconstrictor of pulmonary, coronary, and cerebral arteriole beds. Also stimulates contraction of smooth muscle, such as in bronchi, with possible involvement in asthma. This effect is at least partially mediated through tachykinin release.

Confezionamento

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Altre note

Sales restrictions may apply.

Informazioni sulla sicurezza

• Pittogrammi: GHS08,GHS07
• Avvertenze: Danger
• Indicazioni di pericolo: H302,H360FD
• Consigli di prudenza: P201 - P301 + P312 + P330 - P308 + P313
• Classi di pericolo: Acute Tox. 4 Oral - Repr. 1B
• Codice della classe di stoccaggio: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• Classe di pericolosità dell'acqua (WGK): WGK 3