A4673

Albendazole

analytical standard, ≥98%

• Sinonimo/i: Methyl 5-(propylthio)-2-benzimidazolecarbamate
• Formula empirica (notazione di Hill): C₁₂H₁₅N₃O₂S
• Numero CAS: 54965-21-8
• Peso molecolare: 265.33
• Numero CE: 259-414-7
• Numero MDL: MFCD00083232
• Codice UNSPSC: 41116107
• ID PubChem: 329770859
• NACRES: NA.24

Proprietà

• Grado: analytical standard
• Livello qualitativo: 100
• Saggio: ≥98%
• tecniche: HPLC: suitable; gas chromatography (GC): suitable
• applicazioni: forensics and toxicology; pharmaceutical (small molecule)
• Formato: neat
• Stringa SMILE: CCCSc1ccc2[nH]c(NC(=O)OC)nc2c1
• InChI: 1S/C12H15N3O2S/c1-3-6-18-8-4-5-9-10(7-8)14-11(13-9)15-12(16)17-2/h4-5,7H,3,6H2,1-2H3,(H2,13,14,15,16); HXHWSAZORRCQMX-UHFFFAOYSA-N

Descrizione

Descrizione generale

Albendazole is a benzimidazole derivative used for the treatment of human gastrointestinal helmintiasis. It inhibits microtubule and blocks the glucose uptake that causes depletion of glycogen stores and lowering formation of adinosine triphosphate (ATP) in the larval and adult stages of susceptible parasite.

Chemical structure: benzimidazole

Applicazioni

Albendazole may be used as a reference standard for the determination of albendazole and its major metabolites, albendazole sulphoxide and albendazole sulphone by high-performance liquid chromatography (HPLC) method in mice plasma.

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Azioni biochim/fisiol

Binds to tubulin and inhibits microtubule assembly.

Informazioni sulla sicurezza

• Pittogrammi: GHS08,GHS09
• Avvertenze: Warning
• Indicazioni di pericolo: H361d,H373,H410
• Consigli di prudenza: P202 - P260 - P273 - P280 - P308 + P313 - P391
• Classi di pericolo: Aquatic Acute 1 - Aquatic Chronic 1 - Repr. 2 - STOT RE 2 Oral
• Organi bersaglio: Adrenal gland,Blood,male reproductive organs,spleen
• Codice della classe di stoccaggio: 11 - Combustible Solids
• Classe di pericolosità dell'acqua (WGK): WGK 3
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable
• Dispositivi di protezione individuale: Eyeshields, Gloves, type N95 (US)