58279
Isatoic anhydride
technical, ≥94% (HPLC)
Sinonimo/i:
3,1-Benzoxazine-2,4(1H)-dione, Anthranilic acid N-carboxylic acid anhydride
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About This Item
Formula empirica (notazione di Hill):
C8H5NO3
Numero CAS:
Peso molecolare:
163.13
Beilstein:
136786
Numero CE:
Numero MDL:
Codice UNSPSC:
12162002
ID PubChem:
Densità del vapore
5.6 (vs air)
Grado
technical
Saggio
≥94% (HPLC)
Punto di fusione
233 °C (dec.) (lit.)
Stringa SMILE
O=C1Nc2ccccc2C(=O)O1
InChI
1S/C8H5NO3/c10-7-5-3-1-2-4-6(5)9-8(11)12-7/h1-4H,(H,9,11)
TXJUTRJFNRYTHH-UHFFFAOYSA-N
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Altre note
Review; Reagent for 2-aminobenzoylations
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G.M. Coppola
Synthesis, 505-505 (1980)
M.C. Venuti
Synthesis, 266-266 (1982)
M H Gelb et al.
Journal of medicinal chemistry, 29(4), 585-589 (1986-04-01)
Derivatives of isatoic anhydride were prepared and tested as inhibitors of serine proteases. A number of isatoic anhydrides with positively charged substituents irreversibly inactivated several trypsin-like enzymes and preferentially inactivated trypsin over chymotrypsin. Further selectivity was obtained by introduction of
L Servillo et al.
European journal of biochemistry, 213(1), 583-589 (1993-04-01)
A fluorescent tRNA derivative labeled at 3'-O position of the ultimate adenosine residue by reaction, under mild conditions, of tRNA with isatoic anhydride [3,1-benzoxazine-2,4(1H)-dione] was obtained. The labeling selectivity was determined by several criteria: digestion with RNase, followed by HPLC
E H Ohlstein et al.
Life sciences, 46(3), 181-188 (1990-01-01)
The biosynthesis and modulation of the vasoconstrictor peptide endothelin was studied in the conditioned medium from cultured bovine pulmonary artery endothelial (BPAE) cells. Conditioned medium from cultured BPAE cells produced contraction of isolated rabbit aortic rings. Incubation of BPAE cells
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