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37032

Supelco

Senkirkine

analytical standard

Sinonimo/i:

12-Hydroxy-4-methyl-4,8-secosenecionan-8,11,16-trione, Renardine

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About This Item

Formula empirica (notazione di Hill):
C19H27NO6
Numero CAS:
2318-18-5
Peso molecolare:
365.42
Numero MDL:
MFCD01684247
Codice UNSPSC:
85151701
ID PubChem:
329755593

Grado

analytical standard

Livello qualitativo

100

Durata

limited shelf life, expiry date on the label

tecniche

HPLC: suitable
gas chromatography (GC): suitable

applicazioni

cleaning products
cosmetics
food and beverages
personal care

Formato

neat

Temperatura di conservazione

−20°C

Stringa SMILE

C\C=C1\C[C@@H](C)[C@@](C)(O)C(=O)OCC2=CCN(C)CC[C@@H](OC1=O)C2=O

InChI

1S/C19H27NO6/c1-5-13-10-12(2)19(3,24)18(23)25-11-14-6-8-20(4)9-7-15(16(14)21)26-17(13)22/h5-6,12,15,24H,7-11H2,1-4H3/b13-5-,14-6-/t12-,15-,19-/m1/s1
HPDHKHMHQGCNPE-QLJRNOHWSA-N

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Applicazioni

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Ricostituzione

Dried down, 50 μg/mL after reconstitution with 1 mL of water

Pittogrammi

Skull and crossbonesHealth hazard
GHS06,GHS08

Avvertenze

Danger

Indicazioni di pericolo

H300,H341

Consigli di prudenza

P201 - P301 + P310 + P330

Classi di pericolo

Acute Tox. 1 Oral - Muta. 2

Codice della classe di stoccaggio

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

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Certificati d'analisi (COA)

Lot/Batch Number
SZBF321XV
SZBF089XV
SZBE212XV
SZBC338XV
SZBB335XV

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Senkirkine.
IARC monographs on the evaluation of the carcinogenic risk of chemicals to humans, 31, 231-238 (1983-07-01)
M Bah et al.
Journal of ethnopharmacology, 43(1), 19-30 (1994-06-01)
A study of the hepatotoxic pyrrolizidine alkaloids (PAs) contained in Packera candidissima (Greene) Weber & Löve (Senecio candidissimus Greene), a Mexican medicinal plant used for the treatment of kidney ailments and noted for its antiseptic properties, is reported. Analysis by
J A Glinski et al.
Acta crystallographica. Section C, Crystal structure communications, 44 ( Pt 9), 1593-1598 (1988-09-15)
lambda(Mo K alpha) = 0.71069 A, T = 298 K. Anonamine (I) (12,21-dihydroxy-4-methyl-4,8-secosenecionan-8,11,16-trione): C19H27NO7, Mr = 381.2, monoclinic, C2, a = 24.247 (7), b = 8.766 (2), c = 9.072 (1) A, beta = 99.21 (2) degrees, U = 1903.3
Xiao-Fang Guo et al.
Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials, 34(5), 724-726 (2011-10-01)
To study alkaloids of Senecio scandens growing in Guangdong. The rapid resolution liquid chromatography-electrospray ionization mass spectrometry (RRLC-ESI-MS/MS) was used to analyse alkaloids of Senecio scandens growing in Guangdong, and senkirkine was isolated and purified by silica gel column chromatography.
U Candrian et al.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 22(3), 223-225 (1984-03-01)
Seneciphylline and senkirkine, two pyrrolizidine alkaloids that occur in animal feeds and medicinal herbs, respectively, have been tested for their ability to produce sex-linked recessive lethals in males of Drosophila melanogaster using the Basc test (3-day feeding method). Seneciphylline was
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