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03338

Supelco

α-Arbutin

analytical standard

Sinonimo/i:

4-Hydroxyphenyl α-D-glucopyranoside, Hydroquinone O-α-D-glucopyranoside

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About This Item

Formula empirica (notazione di Hill):
C12H16O7
Numero CAS:
Peso molecolare:
272.25
Beilstein:
89675
Numero MDL:
Codice UNSPSC:
85151701
ID PubChem:
NACRES:
NA.24

Grado

analytical standard

Livello qualitativo

Saggio

≥99% (HPLC and GC)

Durata

limited shelf life, expiry date on the label

applicazioni

cleaning products
cosmetics
food and beverages
personal care

Formato

neat

Temperatura di conservazione

2-8°C

Stringa SMILE

O[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@@H]1OC2=CC=C(O)C=C2

InChI

1S/C12H16O7/c13-5-8-9(15)10(16)11(17)12(19-8)18-7-3-1-6(14)2-4-7/h1-4,8-17H,5H2/t8-,9-,10+,11-,12+/m1/s1
BJRNKVDFDLYUGJ-ZIQFBCGOSA-N

Descrizione generale

α-Arbutin is a glycosylated hydroquinone and an anomer of naturally occurring arbutin. It is a potent inhibitor of tyrosinase, a vital enzyme involved in epidermal melanin biosynthesis. α-Arbutin finds extensive application as a powerful skin-lightening agent in cosmetic industries.

Applicazioni

α-Arbutin may be used as an analytical reference standard for the determination of the analyte in cosmetics by high-performance liquid chromatography with UV detection (HPLC-UV) method.

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable


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Sigma-Aldrich

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Hydroquinone

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Supelco

PHR1469

Hydroquinone

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Sigma-Aldrich

H9003

Hydroquinone

(+)-Catechin analytical standard

Supelco

43412

(+)-Catechin

Tirosinasi lyophilized powder, ≥1000 unit/mg solid

Sigma-Aldrich

T3824

Tirosinasi

Syntheses of arbutin-$\alpha$-glycosides and a comparison of their inhibitory effects with those of $\alpha$-arbutin and arbutin on human tyrosinase
Sugimoto K, et al.
Chemical & Pharmaceutical Bulletin, 51(7), 798-801 (2003)
Syntheses of $\alpha$-arbutin-$\alpha$-glycosides and their inhibitory effects on human tyrosinase
Sugimoto K, et al.
Journal of Bioscience and Bioengineering, 99(3), 272-276 (2005)
Isolation of $\alpha$-arbutin from Xanthomonas CGMCC 1243 fermentation broth by macroporous resin adsorption chromatography
Liu C, et al.
Journal of Chromatography. B, Biomedical Sciences and Applications, 925, 104-109 (2013)
Quantitative determination of $\alpha$-arbutin, $\beta$-arbutin, kojic acid, nicotinamide, hydroquinone, resorcinol, 4-methoxyphenol, 4-ethoxyphenol, and ascorbic acid from skin whitening products by HPLC-UV
Wang YH, et al.
Journal of AOAC (Association of Official Analytical Chemists) International, 98(1), 5-12 (2015)

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