PC165L
Anti-Opioid μ Receptor (384-398) Rabbit pAb
lyophilized, Calbiochem®
Autenticatiper visualizzare i prezzi riservati alla tua organizzazione & contrattuali
About This Item
Codice UNSPSC:
12352203
NACRES:
NA.41
Origine biologica
rabbit
Livello qualitativo
Forma dell’anticorpo
serum
Tipo di anticorpo
primary antibodies
Clone
polyclonal
Forma fisica
lyophilized
non contiene
preservative
Reattività contro le specie
rat
Produttore/marchio commerciale
Calbiochem®
Condizioni di stoccaggio
OK to freeze
Isotipo
IgG
Condizioni di spedizione
ambient
Temperatura di conservazione
−20°C
modifica post-traduzionali bersaglio
unmodified
Informazioni sul gene
rat ... Oprm1(25601)
Descrizione generale
Rabbit polyclonal antibody supplied as lyophilized, undiluted serum. Recognizes the ~44-45 kDa opioid µ receptor protein.
Recognizes the ~44-45 kDa opiod μ receptor in caudate putamen and the dorsal horn of the spinal cord.
This Anti-Opioid µ Receptor (384-398) Rabbit pAb is validated for use in Frozen Sections, Immunoblotting, IF, IP for the detection of Opioid µ Receptor (384-398).
Immunogeno
Rat
a synthetic peptide corresponding to amino acids 384-398 of rat opioid µ receptor
Applicazioni
Frozen Sections (1:500-1:1000, Cy3 technique; 1:3000-1:6000, HRP)
Immunoblotting (1:2000-1:2500; see application references)
Immunofluorescence (1:100-1:200)
Immunoprecipitation (see comments)
Immunoblotting (1:2000-1:2500; see application references)
Immunofluorescence (1:100-1:200)
Immunoprecipitation (see comments)
Attenzione
Toxicity: Highly Toxic (H)
Stato fisico
Undiluted serum.
Ricostituzione
Reconstitute the lyophilized antibody with 100 µl sterile distilled H₂O. Resulting reconstituted solution contains ≤0.1% sodium azide. Be careful to reconstitute the entire contents of the vial; during shipment and handling portions of the lyophilized pellet may have become dislodged and may not be in the bottom of the vial. Following reconstitution, aliquot and freeze (-20°C).
Risultati analitici
Positive Control
Rat caudate putamen or spinal cord (dorsal horn)
Rat caudate putamen or spinal cord (dorsal horn)
Altre note
The specificity was determined by immunolabeling of transfected cells, immunoblotting analysis, and immunoisolation studies. Antibody specificity was examined in the rat caudate putamen and dorsal horn of the spinal cord. Staining is completely eliminated by pre-treatment of antibody with immunogen peptide at a concentration of 10 µg/ml. This antibody has also been reported to work for immunopercipitation. Antibody should be titrated for optimal results in individual systems.
Zaki, P.A., et al. 1996. Annu. Rev. Pharmacol. Toxicol.36, 379.
Arvidsson, U., et al. 1995. J. Neurosci.15, 3328.
Kieffer, B.L. 1995. Cell. Mol. Neurobiol.15, 615-635.
Childers, S.R. 1991. Life Sci.48, 1991.
Arvidsson, U., et al. 1995. J. Neurosci.15, 3328.
Kieffer, B.L. 1995. Cell. Mol. Neurobiol.15, 615-635.
Childers, S.R. 1991. Life Sci.48, 1991.
Note legali
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Non trovi il prodotto giusto?
Prova il nostro Motore di ricerca dei prodotti.
Codice della classe di stoccaggio
10 - Combustible liquids
Classe di pericolosità dell'acqua (WGK)
WGK 1
Punto d’infiammabilità (°F)
Not applicable
Punto d’infiammabilità (°C)
Not applicable
Certificati d'analisi (COA)
Cerca il Certificati d'analisi (COA) digitando il numero di lotto/batch corrispondente. I numeri di lotto o di batch sono stampati sull'etichetta dei prodotti dopo la parola ‘Lotto’ o ‘Batch’.
Possiedi già questo prodotto?
I documenti relativi ai prodotti acquistati recentemente sono disponibili nell’Archivio dei documenti.
Heng Xu et al.
The Journal of pharmacology and experimental therapeutics, 315(1), 248-255 (2005-07-01)
A growing body of literature indicates that chronic morphine exposure alters the expression and function of cytoskeletal proteins in addition to the well established interactions between mu opioid receptors and G proteins. In the present study, we hypothesized that chronic
Belén Gago et al.
Journal of neuroscience research, 91(12), 1533-1540 (2013-09-17)
The peptides dynorphin and enkephalin modulate many physiological processes, such as motor activity and the control of mood and motivation. Their expression in the caudate putamen (CPu) is regulated by dopamine and opioid receptors. The current work was designed to
Heng Xu et al.
Synapse (New York, N.Y.), 61(3), 166-175 (2006-12-08)
Previous studies established that Tyr-D-Ala-Gly-N-Me-Phe-Gly-ol (DAMGO) and (2S,4aR,6aR,7R,9S,10aS,10bR)-9-(Benzoyloxy)-2-(3-furanyl)dodecahydro-6a,10b-dimethyl-4,10-dioxo-2H-naphtho-[2,1-c]pyran-7-carboxylic acid methyl ester (herkinorin) are fully efficacious mu-agonists. Herkinorin (HERK), unlike DAMGO, does not recruit beta-arrestin and promote mu-receptor internalization, even in cells that over express beta-arrestin. We hypothesized that chronic HERK
Alicia Rivera et al.
Cells, 11(1) (2022-01-12)
Long-term exposition to morphine elicits structural and synaptic plasticity in reward-related regions of the brain, playing a critical role in addiction. However, morphine-induced neuroadaptations in the dorsal striatum have been poorly studied despite its key function in drug-related habit learning.
Il team dei nostri ricercatori vanta grande esperienza in tutte le aree della ricerca quali Life Science, scienza dei materiali, sintesi chimica, cromatografia, discipline analitiche, ecc..
Contatta l'Assistenza Tecnica.