MAB312-AF647

Anti-A2B5 Antibody, clone A2B5-105 Antibody, Alexa Fluor^™ 647 Conjugate

clone A2B5-105, from mouse, ALEXA FLUOR^™ 647

• Sinonimo/i: F12A2B5, 105
• Codice UNSPSC: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

Proprietà

• Origine biologica: mouse
• Livello qualitativo: 100
• Coniugato: ALEXA FLUOR^™ 647
• Forma dell’anticorpo: purified immunoglobulin
• Tipo di anticorpo: primary antibodies
• Clone: A2B5-105, monoclonal
• Reattività contro le specie (prevista in base all’omologia): mammals
• tecniche: flow cytometry: suitable; immunocytochemistry: suitable
• Isotipo: IgM
• Condizioni di spedizione: ambient
• modifica post-traduzionali bersaglio: unmodified

Descrizione

Descrizione generale

A2B5 (also known as F12A2B5) is a cell surface ganglioside expressed on developing thymic epithelial cells, oligodendrocyte progenitors, and neuroendocrine cells. It is highly expressed in embryonic and neonatal tissue, but in the adult mammalian brain its expression is restricted mainly to areas that retain neurogenic potential, such as the subventricular zone (SVZ). Hence, A2B5 is considered as a marker for immature glial-committed precursors, which are permanently generated in the SVZ. Its expression is also considered as a marker for various cancers, including astrocytoma, glioma, pancreatic islet tumors, and squamous cell carcinoma. Explants from A2B5+ tumor cells display a typical progenitor morphology and clearly indicate their immature state. Tumors expressing A2B5 antigen exhibit higher rates of recurrence.

Specificità

This monoclonal antibody detects A2B5 in mammalian cells.

Immunogeno

Embryonic chicken retinal cells.

Applicazioni

Anti-A2B5 Antibody, clone A2B5-105, Alexa Fluor^™ 647 Conjugate Cat. No. MAB312-AF647, is a highly specific mouse monoclonal antibody that targets A2B5 and has been tested in Immunocytochemistry and Flow Cytometry.

Flow Cytometry Analysis: 1:400 dilution from a representative lot immunostained the surface of PC12 cells.

The unconjugated antibody (Cat. No. MAB312) is also available for flow cytometry, immunocytochemistry, immunofluorescence, and immunohistochemistry applications.

Qualità

Evaluated by immunocytochemistry of PC12 cells.

Immunocytochemistry Analysis: A 1:100 Dilution of this antibody immunostained the surface of PC12 cells.

Stato fisico

Purified mouse IgM Alexa Fluor^™ 647 conjugate in PBS with 1.5% BSA and 0.05% sodium azide.

Altre note

Concentration: Please refer to lot specific datasheet.

Note legali

ALEXA FLUOR is a trademark of Life Technologies

Informazioni sulla sicurezza

• Codice della classe di stoccaggio: 12 - Non Combustible Liquids
• Classe di pericolosità dell'acqua (WGK): WGK 2