ABT410

Anti-MATN3 Antibody

from rabbit, purified by affinity chromatography

• Sinonimo/i: Matrilin-3
• Codice UNSPSC: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

Proprietà

• Origine biologica: rabbit
• Livello qualitativo: 100
• Forma dell’anticorpo: affinity isolated antibody
• Tipo di anticorpo: primary antibodies
• Clone: polyclonal
• Purificato mediante: affinity chromatography
• Reattività contro le specie: mouse
• tecniche: immunocytochemistry: suitable; western blot: suitable
• N° accesso UniProt: O15232
• Condizioni di spedizione: wet ice
• modifica post-traduzionali bersaglio: unmodified
• Informazioni sul gene: mouse ... Matn3(17182)

Descrizione

Descrizione generale

Matrilin-3 (MATN3) is a major component of the extracellular matrix of cartilage. MATNs are a family of non-collagenous extracellular matrix (ECM) proteins consisting of four known members that have been proposed to play key roles in modulating cellular phenotypes during chondrogenesis of mesenchymal stem cells (MSCs). MATN1 and MATN3 are expressed specifically in cartilage and are among the most up-regulated ECM proteins during chondrogenesis. MATN3 is composed of a single N-terminal von Willebrand Factor A (vWFA) domain followed by four epidermal growth factor (EGF) repeats and a coiled-coil domain whereas MATN1 is composed of two vWFA domains separated by one EGF-like domain. MATN1 or MATN3 may play a role in modulating chondrogenesis during the chondrocyte differentiation process. Mutations of this gene have been associated with variety of inherited chondrodysplasias. Recent studies show that aberrant expression and processing of MATN3 are hallmarks of conventional cartilaginous neoplasms.

Immunogeno

KLH-conjugated synthetic peptide corresponding to the C-terminus of human MATN3.

Applicazioni

Detect MATN3 using this Anti-MATN3 Antibody validated for use in western blotting & ICC.

Immunocytochemistry Analysis: 5 μg/mL from a representative lot detected MATN3 in NIH/3T3 cells.

Qualità

Evaluated by Western Blotting in NIH/3T3 cell lysate.

Western Blotting Analysis: 1 μg/mL of this antibody detected MATN3 in NIH/3T3 cell lysate.

Descrizione del bersaglio

~52 kDa observed. Uncharacterized bands may be observed in some lysate(s).

Altre note

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Informazioni sulla sicurezza

• Codice della classe di stoccaggio: 10 - Combustible liquids
• Classe di pericolosità dell'acqua (WGK): WGK 2
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable