ABN27

Anti-GRIP-1 Antibody, CT

from rabbit, purified by affinity chromatography

• Sinonimo/i: glutamate receptor interacting protein 1, glutamate receptor-interacting protein 1
• Codice UNSPSC: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

Proprietà

• Origine biologica: rabbit
• Livello qualitativo: 100
• Forma dell’anticorpo: affinity isolated antibody
• Tipo di anticorpo: primary antibodies
• Clone: polyclonal
• Purificato mediante: affinity chromatography
• Reattività contro le specie: rat
• Reattività contro le specie (prevista in base all’omologia): mouse (based on 100% sequence homology), human (based on 100% sequence homology), chimpanzee (based on 100% sequence homology)
• tecniche: immunohistochemistry: suitable (paraffin); immunoprecipitation (IP): suitable; western blot: suitable
• N° accesso NCBI: NP_114458
• N° accesso UniProt: P97879
• Condizioni di spedizione: wet ice
• modifica post-traduzionali bersaglio: unmodified
• Informazioni sul gene: rat ... Grip1(84016)

Descrizione

Descrizione generale

Glutamate receptor interacting protein-1 (GRIP-1) is a multi-PDZ domain scaffold protein and a member of the steroid receptor coactivator (SRC) family of proteins. GRIP-1 interacts and maneuvers kinesin heavy chains to dendrites by acting as the power source for AMPA receptors. During initial stages of embryonic development, GRIP-1 is essential for typical cell-matrix interactions.

Specificità

This antibody recognizes GRIP-1 at the C-terminus.

Immunogeno

Epitope: C-terminus

KLH-conjugated linear peptide corresponding to the C-terminus of rat GRIP-1.

Applicazioni

Detect GRIP-1 using this Anti-GRIP-1 Antibody, C-terminus validated for use in WB, IP, IH(P).

Immunoprecipitation Analysis: 10 µg from a previous lot immunoprecipitated GRIP-1 from rat brain cytosol tissue lysate.

Immunohistochemistry Analysis: 1:300 dilution from a previous lot detected GRIP-1 in rat brain cells.

Research Category
Neuroscience

Research Sub Category
Signaling Neuroscience

Qualità

Evaluated by Western Blot in rat brain cytosol tissue lysate.

Western Blot Analysis: 0.05 µg/mL of this antibody detected GRIP-1 on 10 µg of rat brain cytosol tissue lysate.

Descrizione del bersaglio

~121 kDa observed

Linkage

Replaces: 06-986

Stato fisico

Affinity purified

Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

Stoccaggio e stabilità

Stable for 1 year at 2-8°C from date of receipt.

Risultati analitici

Control
Rat brain cytosol tissue lysate

Altre note

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Esclusione di responsabilità

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Informazioni sulla sicurezza

• Codice della classe di stoccaggio: 12 - Non Combustible Liquids
• Classe di pericolosità dell'acqua (WGK): WGK 1
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable