481486

NF-κB SN50M, Cell-Permeable Inactive Control Peptide

An inactive control for SN50 peptide.

• Sinonimo/i: NF-κB SN50M, Cell-Permeable Inactive Control Peptide, (AAVALLPAVLLALLAPVQRNGQKLMP)
• Formula empirica (notazione di Hill): C₁₂₃H₂₁₅N₃₃O₃₀S
• Peso molecolare: 2668.29
• Codice UNSPSC: 12352200
• NACRES: NA.77

Proprietà

• Livello qualitativo: 100
• Saggio: ≥97% (HPLC)
• Forma fisica: lyophilized
• Produttore/marchio commerciale: Calbiochem^®
• Condizioni di stoccaggio: OK to freeze; desiccated (hygroscopic)
• Solubilità: water: 5 mg/mL
• Condizioni di spedizione: ambient
• Temperatura di conservazione: −20°C

Descrizione

Descrizione generale

An inactive control for SN50 peptide (Cat. No. 481480). Corresponds to the SN50 peptide sequence with substitutions of Asn for Lys³⁶³ and Gly for Arg³⁶⁴ in the NLS region. In murine endothelial LE-II cells induced by LPS, this peptide had no measurable effect on NF-κB translocation at 18 µM.

An inactive control for SN50 peptide (Cat. No. 481480). Corresponds to the SN50 peptide sequence with substitutions of Lys³⁶³ for Asn and Arg³⁶⁴ for Gly in the NLS region. In murine endothelial LE-II cells induced by LPS, this peptide had no measurable effect on NF-κB translocation at 18 µM.

Azioni biochim/fisiol

Cell permeable: no

Primary Target
an inactive control for SN50 peptide

Product does not compete with ATP.

Reversible: no

Confezionamento

Yes

Attenzione

Toxicity: Standard Handling (A)

Sequenza

H-Ala-Ala-Val-Ala-Leu-Leu-Pro-Ala-Val-Leu-Leu-Ala-Leu-Leu-Ala-Pro-Val-Gln-Arg-Asn-Gly-Gln-Lys-Leu-Met-Pro-OH

Stato fisico

Supplied as a trifluoroacetate salt.

Ricostituzione

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C. Avoid/freeze thaw cycles of solutions.

Altre note

Lin, Y.-Z., et al. 1995. J. Biol. Chem. 270, 14255.

Note legali

Sold under license of U.S. Patents 5,807,746 and 6,043,339 for research use only. Licenses for commercial manufacture, commercial use, diagnostics, or therapeutics may be obtained by contacting Vanderbilt University, Nashville, Tennessee.

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Informazioni sulla sicurezza

• Codice della classe di stoccaggio: 11 - Combustible Solids
• Classe di pericolosità dell'acqua (WGK): WGK 1
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable