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Merck
Tutte le immagini(1)

Documenti

07-464

Sigma-Aldrich

Anti-Vav3 Antibody, human

Upstate®, from rabbit

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Tutte le immagini(1)

About This Item

Codice UNSPSC:
12352203
eCl@ss:
32160702
NACRES:
NA.41

Origine biologica

rabbit

Livello qualitativo

100

Forma dell’anticorpo

purified immunoglobulin

Tipo di anticorpo

primary antibodies

Clone

polyclonal

Reattività contro le specie

human

Produttore/marchio commerciale

Upstate®

tecniche

immunocytochemistry: suitable
immunohistochemistry: suitable
immunoprecipitation (IP): suitable
western blot: suitable

Isotipo

IgG

N° accesso NCBI

NM_006113

N° accesso UniProt

Q9UKW4

Condizioni di spedizione

wet ice

modifica post-traduzionali bersaglio

unmodified

Informazioni sul gene

human ... VAV3(10451)

Specificità

Vav3

Immunogeno

KLH-conjugated, synthetic peptide corresponding to amino acids 566-591of human Vav3.

Applicazioni

Anti-Vav3 Antibody, human detects level of Vav3 & has been published & validated for use in IP, WB, IC, IH.
Research Category
Signaling
Research Sub Category
Cytoskeletal Signaling

Qualità

routinely evaluated by immunoblot in RIPA lysates from HeLa and Jurkat cells

Descrizione del bersaglio

98 kDa

Stato fisico

0.1M Tris-glycine, pH 7.4, 0.15M NaCl,0.05% sodium azide before the addition of glycerol to 30%
Format: Purified
Protein A purified

Stoccaggio e stabilità

2 years at -20°C

Note legali

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

Esclusione di responsabilità

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Codice della classe di stoccaggio

10 - Combustible liquids

Classe di pericolosità dell'acqua (WGK)

WGK 1

Certificati d'analisi (COA)

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Youjia Cao et al.
The EMBO journal, 21(18), 4809-4819 (2002-09-18)
The Rac/Rho-specific guanine nucleotide exchange factor, Vav-1, is a key component of the T-cell antigen receptor (TCR)-linked signaling machinery. Here we have used somatic cell gene-targeting technology to generate a Vav-1-deficient Jurkat T-cell line. The J.Vav1 cell line exhibits dramatic
Mapping cell-matrix stresses during stretch reveals inelastic reorganization of the cytoskeleton.
Nuria Gavara,Pere Roca-Cusachs,Raimon Sunyer,Ramon Farre,Daniel Navajas
Biophysical Journal null
VAV proteins as signal integrators for multi-subunit immune-recognition receptors.
Turner, Martin and Billadeau, Daniel D
Nature Reviews: Immunology, 2, 476-486 (2002)
Emanuela Dylgjeri et al.
Clinical cancer research : an official journal of the American Association for Cancer Research, 25(18), 5623-5637 (2019-07-04)
DNA-dependent protein kinase catalytic subunit (DNA-PK) is a pleiotropic kinase involved in DNA repair and transcriptional regulation. DNA-PK is deregulated in selected cancer types and is strongly associated with poor outcome. The underlying mechanisms by which DNA-PK promotes aggressive tumor
Mehdi Badaoui et al.
Cell reports, 32(1), 107842-107842 (2020-07-09)
Pseudomonas aeruginosa (Pa) represents the leading cause of airway infection in cystic fibrosis (CF). Early airways colonization can be explained by enhanced adhesion of Pa to the respiratory epithelium. RNA sequencing (RNA-seq) on fully differentiated primary cultures of airway epithelial
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