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F-052

Supelco

Furosemide Impurity Mixture solution

5 μg/mL (50:50 Acetonitrile:Water, each analyte), certified reference material, ampule of 1 mL, Cerilliant®

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About This Item

Formula empirica (notazione di Hill):
C12H11ClN2O5S
Peso molecolare:
330.74
Codice UNSPSC:
12352200
NACRES:
NA.24

Grado

certified reference material

Forma fisica

liquid

Caratteristiche

Snap-N-Spike®/Snap-N-Shoot®

Composizione

2-Chloro-4-furfurylamino-5-sulfamoylbenzoic acid, 5 μg/mL
4-Chloro-5-sulfamoylanthranilic acid (Furosemide RCB), 5 μg/mL
Furosemide, 5 μg/mL

Confezionamento

ampule of 1 mL

Produttore/marchio commerciale

Cerilliant®

Concentrazione

5 μg/mL (50:50 Acetonitrile:Water, each analyte)

tecniche

gas chromatography (GC): suitable
liquid chromatography (LC): suitable

applicazioni

pharmaceutical (small molecule)

Formato

multi-component solution

Temperatura di conservazione

−20°C

Descrizione generale

Furosemide is a powerful diuretic agent with the ascending limb of Henle′s loop of nephron as its primary site of action. It works by preventing the reabsorption of sodium and increasing the secretion of renal vasodilatory prostaglandin E. In combination with nitrates, it is used as the standard treatment for pulmonary edema caused by acute heart failure.

Applicazioni

Furosemide Impurity Mixture solution may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations by chromatography techniques.
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Note legali

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

Analita

Descrizione
    Furosemide, Pharmaceutical Secondary Standard; Certified Reference Material
    Furosemide Related Compound B, Pharmaceutical Secondary Standard; Certified Reference Material
    Furosemide Related Compound A, Pharmaceutical Secondary Standard; Certified Reference Material

Pittogrammi

FlameExclamation mark
GHS02,GHS07

Avvertenze

Danger

Indicazioni di pericolo

H225,H302,H319

Classi di pericolo

Acute Tox. 4 Oral - Eye Irrit. 2 - Flam. Liq. 2

Codice della classe di stoccaggio

3 - Flammable liquids

Classe di pericolosità dell'acqua (WGK)

WGK 2

Punto d’infiammabilità (°F)

50.0 °F

Punto d’infiammabilità (°C)

10 °C

Certificati d'analisi (COA)

Cerca il Certificati d'analisi (COA) digitando il numero di lotto/batch corrispondente. I numeri di lotto o di batch sono stampati sull'etichetta dei prodotti dopo la parola ‘Lotto’ o ‘Batch’.

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Furosemide effect on isolated perfused tubules
Burg M, et al.
The American Journal of Physiology, 225(1), 119-124 (1973)
Lack of renoprotective effects of dopamine and furosemide during cardiac surgery
Lassnigg A, et al.
Journal of the American Society of Nephrology, 11(1), 97-104 (2000)
Randomised trial of high-dose isosorbide dinitrate plus low-dose furosemide versus high-dose furosemide plus low-dose isosorbide dinitrate in severe pulmonary oedema
Cotter G, et al.
Lancet, 351(9100), 389-393 (1998)
Furosemide
USP42/NF37: United States Pharmacopeia and National Formulary
United States Pharmacopeia/National Formulary, 41(3), 2006-2006 (2018)

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