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855475P

Avanti

12:0 Lyso PC

1-lauroyl-2-hydroxy-sn-glycero-3-phosphocholine, powder

Sinonimo/i:

1-dodecanoyl-sn-glycero-3-phosphocholine; PC(12:0/0:0)

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About This Item

Formula empirica (notazione di Hill):
C20H42NO7P
Numero CAS:
20559-18-6
Peso molecolare:
439.52
Numero MDL:
MFCD00133434
Codice UNSPSC:
51191904
NACRES:
NA.25

Saggio

>99% (LPC; may contain up to 10% of the 2-LPC isomer, TLC)

Stato

powder

Confezionamento

pkg of 1 × 200 mg (855475P-200mg)
pkg of 1 × 25 mg (855475P-25mg)
pkg of 1 × 500 mg (855475P-500mg)

Produttore/marchio commerciale

Avanti Research™ - A Croda Brand 855475P

Condizioni di spedizione

dry ice

Temperatura di conservazione

−20°C

Stringa SMILE

O[C@](COP([O-])(OCC[N+](C)(C)C)=O)([H])COC(CCCCCCCCCCC)=O

InChI

1S/C20H42NO7P/c1-5-6-7-8-9-10-11-12-13-14-20(23)26-17-19(22)18-28-29(24,25)27-16-15-21(2,3)4/h19,22H,5-18H2,1-4H3/t19-/m1/s1
BWKILASWCLJPBO-LJQANCHMSA-N

Descrizione generale

Lyso-phosphatidylcholine (LPC) is a bioactive proinflammatory lipid secreted on pathological response. It has a choline group at its polar head. Lysophosphatidylcholine (Lyso-PC) is a component of blood plasma, vascular tissue and lipoproteins.

Applicazioni

12:0 Lyso PC has been used to study its neuritogenic activity and the applications of exogenous lipids.

Azioni biochim/fisiol

Lysophosphatidylcholine (LPC) alters various functions in different cell-types, like endothelial cells, smooth muscle cells, monocytes, macrophages and T-cells. It is associated with atherosclerosis and inflammatory diseases. LPC activates many second messengers including, protein kinase C, extracellular-signal-regulated kinases and protein tyrosine kinases.

Confezionamento

20 mL Clear Glass Screw Cap Vial (855475P-500mg)
5 mL Amber Glass Screw Cap Vial (855475P-200mg)
5 mL Amber Glass Screw Cap Vial (855475P-25mg)

Note legali

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

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Certificati d'analisi (COA)

Lot/Batch Number

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I documenti relativi ai prodotti acquistati recentemente sono disponibili nell’Archivio dei documenti.

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Inner/outer nuclear membrane fusion in nuclear pore assembly: biochemical demonstration and molecular analysis
Fichtman B, et al.
Molecular Biology of the Cell, 21(23) (2010)
Secretory phospholipases A2 induce neurite outgrowth in PC12 cells through lysophosphatidylcholine generation and activation of G2A receptor
Ikeno Y, et al.
Test, 280(30) (2005)
Boris Fichtman et al.
Molecular biology of the cell, 21(23), 4197-4211 (2010-10-12)
Nuclear pore complexes (NPCs) are large proteinaceous channels embedded in double nuclear membranes, which carry out nucleocytoplasmic exchange. The mechanism of nuclear pore assembly involves a unique challenge, as it requires creation of a long-lived membrane-lined channel connecting the inner
Shi-Yuan Wen et al.
Phytomedicine : international journal of phytotherapy and phytopharmacology, 69, 152690-152690 (2018-11-06)
Rhodioloside is a glucoside of tyrosol isolated from Rhodiola rosea. However, its regulating effect on hepatic dyslipidemia of atherogenic mice has rarely been studied. The specific aims of current study included to clarify lipidomic perturbation in liver tissues of apolipoprotein
Lysophosphatidylcholine stimulates the release of arachidonic acid in human endothelial cells
Wong JT, et al.
Test, 273(12), 6830-6836 (1998)
Visualizza tutti i documenti correlati

Articoli

Critical Micelle Concentrations (CMCs) - Avanti® Polar Lipids

The critical micelle concentration (CMC) can be approximately defined as the lipid monomer concentration at which appreciable amounts (>5% of total) of micellar aggregates first begin to appear in the equilibrium: nM1<=>Mn

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