694746

Bis(3,5-di(trifluoromethyl)phenyl)chlorophosphine

• Sinonimo/i: P,P-Bis[3,5-bis(trifluoromethyl)phenyl]phosphinous chloride
• Formula empirica (notazione di Hill): C₁₆H₆ClF₁₂P
• Numero CAS: 142421-57-6
• Peso molecolare: 492.63
• Numero MDL: MFCD01630852
• Codice UNSPSC: 12352002
• ID PubChem: 329761683
• NACRES: NA.22

Proprietà

• Forma fisica: solid
• Impiego in reazioni chimiche: reaction type: Buchwald-Hartwig Cross Coupling Reaction; reaction type: Heck Reaction; reaction type: Hiyama Coupling; reaction type: Negishi Coupling; reaction type: Sonogashira Coupling; reaction type: Stille Coupling; reaction type: Suzuki-Miyaura Coupling; reagent type: ligand
• Punto di fusione: 25-29 °C
• Gruppo funzionale: phosphine
• Stringa SMILE: FC(F)(F)c1cc(cc(c1)C(F)(F)F)P(Cl)c2cc(cc(c2)C(F)(F)F)C(F)(F)F
• InChI: 1S/C16H6ClF12P/c17-30(11-3-7(13(18,19)20)1-8(4-11)14(21,22)23)12-5-9(15(24,25)26)2-10(6-12)16(27,28)29/h1-6H; DFZQEHBNAJGDCT-UHFFFAOYSA-N

Descrizione

Applicazioni

Reactant for synthesis of:

• Chiral phosphine-aminophosphine ligands for rhodium-catalyzed asymmetric hydrogenation
• Ligands for palladium-catalyzed stereoselective allylation reactions
• Ligands for enantioselective hydrogenations
• Josiphos analog as catalyst for asymmetric hydrogenation
• Ligands used in asymmetric hydrovinylation reactions

Reactant for enantioselective hydrogenation reactions catalyzed by Ru-(phosphine-oxazoline) complexes

Informazioni sulla sicurezza

• Pittogrammi: GHS02,GHS05
• Avvertenze: Danger
• Indicazioni di pericolo: H261,H314
• Consigli di prudenza: P231 + P232 - P280 - P305 + P351 + P338 - P310 - P422
• Classi di pericolo: Skin Corr. 1B - Water-react 3
• Codice della classe di stoccaggio: 4.3 - Hazardous materials which set free flammable gases upon contact with water
• Classe di pericolosità dell'acqua (WGK): WGK 3
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable
• Dispositivi di protezione individuale: Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges