415057

Magnesium stearate

technical grade

• Sinonimo/i: Stearic acid magnesium salt
• Formula condensata: [CH₃(CH₂)₁₆CO₂]₂Mg
• Numero CAS: 557-04-0
• Peso molecolare: 591.24
• Beilstein: 3919702
• Numero CE: 209-150-3
• Numero MDL: MFCD00036391
• Codice UNSPSC: 12352100
• ID PubChem: 24865972
• NACRES: NA.22

Proprietà

• Grado: technical grade
• Forma fisica: powder
• Composizione: palmitate salt, 25% ; stearate salt, 65%
• Punto di fusione: 200 °C (lit.)
• Stringa SMILE: CCCCCCCCCCCCCCCCCC(=O)O[Mg]OC(=O)CCCCCCCCCCCCCCCCC
• InChI: 1S/2C18H36O2.Mg/c2*1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18(19)20;/h2*2-17H2,1H3,(H,19,20);/q;;+2/p-2; HQKMJHAJHXVSDF-UHFFFAOYSA-L

Descrizione

Descrizione generale

Magnesium stearate (Mg-St) is the magnesium salt of stearic acid. Its anhydrate, dihydrate and trihydrate forms have been prepared. The tabletting of the blends of magnesium stearate and lactose granules has been described. The influence of mixing time on hardness, disintegration time and ejection force on the compressed tablets was examined. Mg-St is widely used lubricant in pharmaceutical industry. It also plays a role in delaying the process of dissolution. Its detection in tablets by laser-induced breakdown spectroscopy has been proposed.

Magnesium stearate, the salt of stearic acid, is widely employed as an inactive component in making pharmaceutical tablets.

Applicazioni

Magnesium stearate may be used as excipient in the formulations of diclofenac sodium tablets. It may be used for the preparation of tramadol HCl matrix tablets.

Informazioni sulla sicurezza

• Codice della classe di stoccaggio: 11 - Combustible Solids
• Classe di pericolosità dell'acqua (WGK): nwg
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable
• Dispositivi di protezione individuale: dust mask type N95 (US), Eyeshields, Gloves