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157201

Sigma-Aldrich

Sodium aurothiomalate hydrate

Sinonimo/i:

(1,2-Dicarboxyethylthio)gold disodium salt hydrate, Gold sodium thiomalate hydrate, Mercaptobutanedioic acid gold(I) disodium salt

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About This Item

Formula condensata:
NaO2CCH2CH(SAu)CO2Na · xH2O
Peso molecolare:
390.08 (anhydrous basis)
Numero MDL:
MFCD00166971
Codice UNSPSC:
12352100
ID PubChem:
24849665
NACRES:
NA.22

Forma fisica

powder

Stringa SMILE

O.[Na+].[Na+].[O-]C(=O)CC(S[Au])C([O-])=O

InChI

1S/C4H6O4S.Au.2Na.H2O/c5-3(6)1-2(9)4(7)8;;;;/h2,9H,1H2,(H,5,6)(H,7,8);;;;1H2/q;3*+1;/p-3
YLQOAPBVYJCTPW-UHFFFAOYSA-K

Categorie correlate

Descrizione generale

Sodium aurothiomalate has antirheumatic properties and exhibits inhibitory effects against M. tuberculosis.

Applicazioni

Sodium aurothiomalate hydrate was used in the high mobility group box chromosomal protein 1 (HMGB1) western blotting.

Pittogrammi

Exclamation mark
GHS07

Avvertenze

Warning

Indicazioni di pericolo

H317

Consigli di prudenza

P280

Classi di pericolo

Skin Sens. 1

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Certificati d'analisi (COA)

Cerca il Certificati d'analisi (COA) digitando il numero di lotto/batch corrispondente. I numeri di lotto o di batch sono stampati sull'etichetta dei prodotti dopo la parola ‘Lotto’ o ‘Batch’.

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Sigma-Aldrich

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Gold nanoparticles 20 nm diameter, OD 1, stabilized suspension in 0.1 mM PBS, reactant free

Sigma-Aldrich

753610

Gold nanoparticles

Antischiuma EX-CELL® gamma irradiated

SAFC

59920C

Antischiuma EX-CELL®

Cecilia K Zetterström et al.
Journal of leukocyte biology, 83(1), 31-38 (2007-10-05)
Gold compounds such as gold sodium thiomalate (GST) can reduce the symptoms of rheumatoid arthritis (RA), although their mechanism of action is not well defined. As the proinflammatory mediator high mobility group box chromosomal protein 1 (HMGB1) may play a
Kathryn E A Lougheed et al.
Tuberculosis (Edinburgh, Scotland), 89(5), 364-370 (2009-08-25)
Mycobacterium tuberculosis has an on-going impact on global public health and new therapeutics to treat tuberculosis are urgently required. The emergence of drug resistant tuberculosis poses a serious threat to the control of this pathogen, and the development of drugs
Christoph Tabeling et al.
Journal of vascular research, 52(4), 279-288 (2016-02-20)
Pulmonary vascular hyperresponsiveness is a main characteristic of pulmonary arterial hypertension (PAH). In PAH patients, elevated levels of the vasoconstrictors thromboxane A2 (TXA2), endothelin (ET)-1 and serotonin further contribute to pulmonary hypertension. Protein kinase C (PKC) isozyme alpha (PKCα) is
Meghan Riddell et al.
Nature communications, 9(1), 5357-5357 (2018-12-19)
Strict regulation of proliferation is vital for development, whereas unregulated cell proliferation is a fundamental characteristic of cancer. The polarity protein atypical protein kinase C lambda/iota (aPKCλ) is associated with cell proliferation through unknown mechanisms. In endothelial cells, suppression of
Farivash Darabi et al.
Journal of inorganic biochemistry, 149, 102-107 (2015-04-14)
Aurothiomalate (AuTm) is an old, clinically established, antiarthritic gold drug that is currently being reconsidered as a candidate drug for cancer treatment and for other therapeutic indications within a more general drug repositioning program. As the biological effects of gold

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