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Merck

SCN8A

sodium channel, voltage gated, type VIII, alpha subunit

Sinonimi:
CERIII, CIAT, EIEE13, MED, NaCh6, Nav1.6, PN4
Specie:
Human SCN8A (6334), Mouse Scn8a (20273), Rat Scn8a (29710), chicken SCN8A (100857835), dog SCN8A (477604), Horse SCN8A (100052777), cow SCN8A (537277), naked mole-rat Scn8a (101711868), domestic guinea pig Scn8a (100734003), sheep SCN8A (101113744) ...Più
ID UniProtKB:
Q9UQD0, B9VWG8, O95788, Q9NYX2, Q9UPB2
ID gene:
  • Human(6334) Summary: This gene encodes a member of the sodium channel alpha subunit gene family. The encoded protein forms the ion pore region of the voltage-gated sodium channel. This protein is essential for the rapid membrane depolarization that occurs during the formation of the action potential in excitable neurons. Mutations in this gene are associated with mental retardation, pancerebellar atrophy and ataxia. Alternate splicing results in multiple transcript variants.[provided by RefSeq, May 2010]
  • Mouse(20273) sodium channel, voltage-gated, type VIII, alpha
  • Rat(29710) sodium channel, voltage gated, type VIII, alpha subunit
  • chicken(100857835) sodium channel, voltage gated, type VIII, alpha subunit
  • dog(477604) sodium channel, voltage gated, type VIII, alpha subunit
  • Horse(100052777) sodium channel, voltage gated, type VIII, alpha subunit
  • cow(537277) sodium channel, voltage gated, type VIII, alpha subunit
  • naked mole-rat(101711868) sodium channel, voltage gated, type VIII, alpha subunit
  • domestic guinea pig(100734003) sodium channel, voltage gated, type VIII, alpha subunit
  • sheep(101113744) sodium channel, voltage gated, type VIII, alpha subunit
  • domestic cat(101096578) sodium channel, voltage gated, type VIII, alpha subunit
  • chicken(426869) sodium channel, voltage gated, type VIII, alpha subunit

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Antibodies

N° Catalogo
Descrizione
Reattività con
Applicazione
WH0006334M4
Monoclonal Anti-SCN8A antibody produced in mouse, clone 4G7, purified immunoglobulin, buffered aqueous solution,
Reattività con
human, mouse, rat
Applicazione
ELISA
immunofluorescence
western blot
AB5580
Anti-SCN8A Sodium Channel Antibody, Chemicon®, from rabbit,
Reattività con
mouse, rat
Applicazione
immunocytochemistry
immunohistochemistry
western blot
SAB2108709
Anti-SCN8A, affinity isolated antibody,
Reattività con
bovine, dog, guinea pig, horse, human, mouse, rabbit, rat
Applicazione
western blot
HPA043937
Anti-SCN8A antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reattività con
human
Applicazione
immunofluorescence
HPA073590
Anti-SCN8A antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reattività con
human
Applicazione
immunofluorescence

Small Molecule - Blocker

N° Catalogo
Descrizione
Specie
L5647
Lidocaine hydrochloride monohydrate, solid,
Specie
human
P9879
Procaine hydrochloride, ≥97%,
Specie
human
1366013
Lidocaine hydrochloride, United States Pharmacopeia (USP) Reference Standard,
Specie
human
1366002
Lidocaine, United States Pharmacopeia (USP) Reference Standard,
Specie
human
SML2088
Procainamide hydrochloride, ≥98% (HPLC),
Specie
human

esiRNA

N° Catalogo
Descrizione
Specie
EMU187341
MISSION® esiRNA, targeting mouse Scn8a,
Specie
mouse