PPARA
peroxisome proliferator-activated receptor alpha
Sinonimi:
NR1C1, PPAR, PPARalpha, hPPAR
Specie:
Human PPARA (5465), Mouse Ppara (19013), Rat Ppara (25747), domestic guinea pig Ppara (100135604), chicken PPARA (374120), naked mole-rat Ppara (101725514), Domestic Rabbit PPARA (100009308), Goat PPARA (100861393), sheep PPARA (100190976), dog PPARA (403654) ...Più
ID UniProtKB:
ID gene:
- Human(5465) Summary: Peroxisome proliferators include hypolipidemic drugs, herbicides, leukotriene antagonists, and plasticizers; this term arises because they induce an increase in the size and number of peroxisomes. Peroxisomes are subcellular organelles found in plants and animals that contain enzymes for respiration and for cholesterol and lipid metabolism. The action of peroxisome proliferators is thought to be mediated via specific receptors, called PPARs, which belong to the steroid hormone receptor superfamily. PPARs affect the expression of target genes involved in cell proliferation, cell differentiation and in immune and inflammation responses. Three closely related subtypes (alpha, beta/delta, and gamma) have been identified. This gene encodes the subtype PPAR-alpha, which is a nuclear transcription factor. Multiple alternatively spliced transcript variants have been described for this gene, although the full-length nature of only two has been determined. [provided by RefSeq, Jul 2008]
- Mouse(19013) peroxisome proliferator activated receptor alpha
- Rat(25747) peroxisome proliferator activated receptor alpha
- domestic guinea pig(100135604) peroxisome proliferator activated receptor alpha
- chicken(374120) peroxisome proliferator-activated receptor alpha
- naked mole-rat(101725514) peroxisome proliferator-activated receptor alpha
- Domestic Rabbit(100009308) peroxisome proliferator-activated receptor alpha
- Goat(100861393) peroxisome proliferator-activated receptor alpha
- sheep(100190976) peroxisome proliferator-activated receptor alpha
- dog(403654) peroxisome proliferator-activated receptor alpha
- Horse(100049840) peroxisome proliferator-activated receptor alpha
- domestic cat(101095837) peroxisome proliferator-activated receptor alpha
- domestic cat(100049013) peroxisome proliferator-activated receptor alpha
- cow(281992) peroxisome proliferator-activated receptor alpha
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Small Molecule - Activator
Small Molecule - Agonist
Numero di prodotto
Descrizione
Specie
Fenofibrate Related Compound B, United States Pharmacopeia (USP) Reference Standard,
Specie
human
Small Molecule - Antagonist
Antibodies
Numero di prodotto
Descrizione
Reattività con
Applicazione
Anti-PPAR-α antibody produced in rabbit, affinity isolated antibody,
Reattività con
human, mouse, rat
Applicazione
ELISA
immunofluorescence
western blot
immunofluorescence
western blot
Anticorpo anti-PPAR α, ascites fluid, Chemicon®,
Reattività con
human, mouse
Applicazione
ELISA
immunocytochemistry
western blot
immunocytochemistry
western blot
Anti-PPARα Antibody, clone 4G22 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Reattività con
bovine, canine, feline, human, monkey, mouse, porcine, rat
Applicazione
affinity binding assay
immunocytochemistry
immunohistochemistry
western blot
immunocytochemistry
immunohistochemistry
western blot
Anti-phospho PPAR alpha (Ser73), from rabbit,
Reattività con
bovine, human, mouse, rat
Applicazione
dot blot
immunocytochemistry
immunofluorescence
immunohistochemistry
western blot
immunocytochemistry
immunofluorescence
immunohistochemistry
western blot
Anti-PPARA antibody produced in rabbit, affinity isolated antibody,
Reattività con
human, rat
Applicazione
western blot
Proteins
Numero di prodotto
Descrizione
Specie
PPARα, ligand binding domain (170-468) human, recombinant, expressed in E. coli, ≥80% (SDS-PAGE),
Specie
human
PPARα isotype, GST tagged human, recombinant, expressed in E. coli, ≥70% (SDS-PAGE),
Specie
human
PPARα isotype, ligand binding domain, GST tagged human, recombinant, expressed in E. coli, ≥80% (SDS-PAGE),
Specie
human
esiRNA
Numero di prodotto
Descrizione
Specie