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Merck

ITGAV

integrin, alpha V

Sinonimi:
CD51, MSK8, VNRA, VTNR
Specie:
ID UniProtKB:
ID gene:
  • Human(3685) Summary: This gene encodes a protein that is a member of the integrin superfamily. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This protein undergoes post-translational cleavage to yield disulfide-linked heavy and light chains that combine with multiple integrin beta chains to form different integrins. This protein has been shown to heterodimerize with beta 1, beta 3, beta 5, beta 6, and beta 8; the heterodimer of alpha v and beta 3 is the Vitronectin receptor. This protein interacts with several extracellular matrix proteins to mediate cell adhesion and may play a role in cell migration. It is proposed that this protein may regulate angiogenesis and cancer progression. Alternative splicing results in multiple transcript variants that encode different protein isoforms. [provided by RefSeq, May 2013]
  • Mouse(16410) integrin alpha V
  • Rat(296456) integrin, alpha V
  • dog(488437) integrin, alpha V
  • naked mole-rat(101717672) integrin, alpha V
  • domestic guinea pig(100728575) integrin, alpha V
  • domestic cat(101085820) integrin, alpha V
  • chicken(396420) integrin, alpha V
  • Zebrafish(100151255) integrin, alpha V
  • Domestic Rabbit(100008956) integrin, alpha V
  • cow(281875) integrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51)
  • sheep(443143) integrin, alpha V
  • Horse(100068706) integrin, alpha V

Custom & Knockdown Gene Products

Small Molecule - Antagonist

Numero di prodotto
Descrizione
Specie
Gly-Arg-Gly-Asp-Ser-Pro-Lys, ≥97% (HPLC),
Specie
human

Antibodies

Numero di prodotto
Descrizione
Reattività con
Applicazione
Anticorpo anti-integrina αVβ3, clone LM609, clone LM609, Chemicon®, from mouse,
Reattività con
avian, bovine, canine, chicken, human, monkey, pig, rabbit
Applicazione
flow cytometry
immunofluorescence

immunohistochemistry

immunoprecipitation (IP)
Anticorpo anti-integrina αVβ6, clone 10D5, privo di azoturi, clone 10D5, Chemicon®, from mouse,
Reattività con
human, mouse, rat
Applicazione
flow cytometry
immunoprecipitation (IP)
Anticorpo anti-integrina αVβ5, clone P1F6, clone P1F6, Chemicon®, from mouse,
Reattività con
chicken, human
Applicazione
flow cytometry
immunocytochemistry

immunohistochemistry

immunoprecipitation (IP)
Anti-Integrin αVβ8 Antibody, clone EM13309 , ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Reattività con
human
Applicazione
flow cytometry
immunocytochemistry

immunohistochemistry

western blot
Anti-Integrin alpha5 (Preservative Free) Antibody, clone SNAKA51, clone SNAKA51, from mouse, purified by using protein G,
Reattività con
human
Applicazione
activity assay
immunocytochemistry

western blot

Proteins

Numero di prodotto
Descrizione
Specie
Human Integrin αVβ3 Protein, Triton X-100 Formulation, ,
Specie
human
Human Integrin αVβ3, Octyl-β-D-glucopyranoside Formulation, ,
Specie
human

esiRNA

Numero di prodotto
Descrizione
Specie
MISSION® esiRNA, targeting mouse Itgav,
Specie
mouse
MISSION® esiRNA, targeting human ITGAV,
Specie
human