GP1BA
glycoprotein Ib (platelet), alpha polypeptide
Sinonimi:
BDPLT1, BDPLT3, BSS, CD42B, CD42b-alpha, DBPLT3, GP1B, GPIbA, VWDP
Specie:
Human GP1BA (2811), Mouse Gp1ba (14723), Rat Gp1ba (691992), chicken GP1BA (420059), naked mole-rat Gp1ba (101717127), domestic guinea pig Gp1ba (100717535), sheep GP1BA (101109891), cow GP1BA (504977), domestic cat GP1BA (101092307), dog GP1BA (403638)
ID UniProtKB:
ID gene:
- Human(2811) Summary: Glycoprotein Ib (GP Ib) is a platelet surface membrane glycoprotein composed of a heterodimer, an alpha chain and a beta chain, that is linked by disulfide bonds. The Gp Ib functions as a receptor for von Willebrand factor (VWF). The complete receptor complex includes noncovalent association of the alpha and beta subunits with platelet glycoprotein IX and platelet glycoprotein V. The binding of the GP Ib-IX-V complex to VWF facilitates initial platelet adhesion to vascular subendothelium after vascular injury, and also initiates signaling events within the platelet that lead to enhanced platelet activation, thrombosis, and hemostasis. This gene encodes the alpha subunit. Several polymorphisms and mutations have been described in this gene, some of which are the cause of Bernard-Soulier syndromes and platelet-type von Willebrand disease. [provided by RefSeq, Mar 2010]
- Mouse(14723) glycoprotein 1b, alpha polypeptide
- Rat(691992) glycoprotein Ib (platelet), alpha polypeptide
- chicken(420059) glycoprotein Ib (platelet), alpha polypeptide
- naked mole-rat(101717127) glycoprotein Ib (platelet), alpha polypeptide
- domestic guinea pig(100717535) glycoprotein Ib (platelet), alpha polypeptide
- sheep(101109891) glycoprotein Ib (platelet), alpha polypeptide
- cow(504977) glycoprotein Ib (platelet), alpha polypeptide
- domestic cat(101092307) glycoprotein Ib (platelet), alpha polypeptide
- dog(403638) glycoprotein Ib (platelet), alpha polypeptide
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ELISA
N° Catalogo
Descrizione
Specie
Antibodies
N° Catalogo
Descrizione
Reattività con
Applicazione
Anti-CD42B antibody, Rabbit monoclonal, recombinant, expressed in proprietary host, clone SP219, affinity isolated antibody,
Reattività con
dog, human, mouse
Applicazione
flow cytometry
immunohistochemistry
immunohistochemistry
Monoclonal Anti-CD42b antibody produced in mouse, clone HIP1, purified immunoglobulin, buffered aqueous solution,
Reattività con
human, nonhuman primates
Applicazione
flow cytometry
Anti-GP1BA antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reattività con
human
Applicazione
immunohistochemistry
Monoclonal Anti-CD42b antibody produced in mouse, clone AK2,
Reattività con
human
Applicazione
flow cytometry
Anti-CD42b/GP1BA Antibody, clone 1C9 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Reattività con
human
Applicazione
affinity binding assay
immunocytochemistry
western blot
immunocytochemistry
western blot