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Merck

DHCR24

24-dehydrocholesterol reductase

Sinonimi:
DCE, Nbla03646, SELADIN1, seladin-1
Specie:
ID UniProtKB:
ID gene:
  • Human(1718) Summary: This gene encodes a flavin adenine dinucleotide (FAD)-dependent oxidoreductase which catalyzes the reduction of the delta-24 double bond of sterol intermediates during cholesterol biosynthesis. The protein contains a leader sequence that directs it to the endoplasmic reticulum membrane. Missense mutations in this gene have been associated with desmosterolosis. Also, reduced expression of the gene occurs in the temporal cortex of Alzheimer disease patients and overexpression has been observed in adrenal gland cancer cells. [provided by RefSeq, Jul 2008]
  • Mouse(74754) 24-dehydrocholesterol reductase
  • Rat(298298) 24-dehydrocholesterol reductase
  • domestic guinea pig(100714000) 24-dehydrocholesterol reductase
  • naked mole-rat(101703975) 24-dehydrocholesterol reductase
  • dog(489573) 24-dehydrocholesterol reductase
  • domestic cat(101098730) 24-dehydrocholesterol reductase
  • Horse(100034055) 24-dehydrocholesterol reductase
  • cow(533726) 24-dehydrocholesterol reductase
  • sheep(101123162) 24-dehydrocholesterol reductase
  • Zebrafish(494102) 24-dehydrocholesterol reductase
  • chicken(424661) 24-dehydrocholesterol reductase

Custom & Knockdown Gene Products

Antibodies

Numero di prodotto
Descrizione
Reattività con
Applicazione
Anti-DHCR24 antibody produced in rabbit, affinity isolated antibody,
Reattività con
bovine, human, mouse, rabbit, rat
Applicazione
western blot
Anti-DHCR24 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reattività con
human
Applicazione
immunohistochemistry
western blot
Anti-DHCR24 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Reattività con
human
Applicazione
immunohistochemistry

Small Molecule - Inhibitor

Numero di prodotto
Descrizione
Specie
Triparanol, ≥97% (HPLC), powder,
Specie
human

esiRNA

Numero di prodotto
Descrizione
Specie
MISSION® esiRNA, targeting human DHCR24,
Specie
human
MISSION® esiRNA, targeting mouse Dhcr24,
Specie
mouse