Passa al contenuto
Merck

CYP46A1

cytochrome P450, family 46, subfamily A, polypeptide 1

Sinonimi:
CP46, CYP46
Specie:
Human CYP46A1 (10858), Mouse Cyp46a1 (13116), Rat Cyp46a1 (362782), chicken CYP46A1 (423450), Zebrafish cyp46a1 (553543), cow CYP46A1 (506438), dog CYP46A1 (480432)
ID UniProtKB:
Q9Y6A2
ID gene:
  • Human(10858) Summary: This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This endoplasmic reticulum protein is expressed in the brain, where it converts cholesterol to 24S-hydroxycholesterol. While cholesterol cannot pass the blood-brain barrier, 24S-hydroxycholesterol can be secreted in the brain into the circulation to be returned to the liver for catabolism. [provided by RefSeq, Jul 2008]
  • Mouse(13116) cytochrome P450, family 46, subfamily a, polypeptide 1
  • Rat(362782) cytochrome P450, family 46, subfamily a, polypeptide 1
  • chicken(423450) cytochrome P450, family 46, subfamily A, polypeptide 1
  • Zebrafish(553543) cytochrome P450, family 46, subfamily A, polypeptide 1
  • cow(506438) cytochrome P450, family 46, subfamily A, polypeptide 1
  • dog(480432) cytochrome P450, family 46, subfamily A, polypeptide 1

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Antibodies

N° Catalogo
Descrizione
Reattività con
Applicazione
MAB2259
Anti-Cholesterol-24 Hydroxylase Antibody, clone1A7, clone 1A7, from mouse,
Reattività con
human, mouse, rabbit, rat
Applicazione
immunocytochemistry
immunohistochemistry
immunoprecipitation (IP)
western blot
SAB1410134
Anti-CYP46A1 antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
Reattività con
human
Applicazione
western blot
SAB2100523
Anti-CYP46A1 antibody produced in rabbit, affinity isolated antibody,
Reattività con
bovine, dog, goat, guinea pig, horse, human, mouse, rat
Applicazione
western blot
SAB1404872
Monoclonal Anti-CYP46A1 antibody produced in mouse, clone 2B5, purified immunoglobulin, buffered aqueous solution,
Reattività con
human
Applicazione
ELISA
immunoprecipitation (IP)
western blot
ZRB2671
Anti-CYP46A1 Antibody, clone 1C20 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Reattività con
human, monkey, mouse
Applicazione
affinity binding assay
immunocytochemistry
immunohistochemistry
western blot

esiRNA

N° Catalogo
Descrizione
Specie
EHU130401
MISSION® esiRNA, targeting human CYP46A1,
Specie
human
EMU041091
MISSION® esiRNA, targeting mouse Cyp46a1,
Specie
mouse