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Merck

CXCR4

chemokine (C-X-C motif) receptor 4

Sinonimi:
CD184, D2S201E, FB22, HM89, HSY3RR, LAP3, LCR1, LESTR, NPY3R, NPYR, NPYRL, NPYY3R, WHIM
Specie:
ID UniProtKB:
ID gene:
  • Human(7852) Summary: This gene encodes a CXC chemokine receptor specific for stromal cell-derived factor-1. The protein has 7 transmembrane regions and is located on the cell surface. It acts with the CD4 protein to support HIV entry into cells and is also highly expressed in breast cancer cells. Mutations in this gene have been associated with WHIM (warts, hypogammaglobulinemia, infections, and myelokathexis) syndrome. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]
  • Mouse(12767) chemokine (C-X-C motif) receptor 4
  • Rat(60628) chemokine (C-X-C motif) receptor 4
  • cow(281736) chemokine (C-X-C motif) receptor 4
  • domestic guinea pig(100731341) chemokine (C-X-C motif) receptor 4
  • dog(483900) chemokine (C-X-C motif) receptor 4
  • naked mole-rat(101699254) chemokine (C-X-C motif) receptor 4
  • sheep(443532) neuropeptide Y receptor type 3
  • chicken(395324) chemokine (C-X-C motif) receptor 4
  • Domestic Rabbit(100346189) chemokine (C-X-C motif) receptor 4
  • domestic cat(493676) chemokine (C-X-C motif) receptor 4

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Antibodies

N° Catalogo
Descrizione
Reattività con
Applicazione
Anti-C-X-C Chemokine Receptor 4 Antibody, NT, Chemicon®, from rabbit,
Reattività con
human
Applicazione
immunocytochemistry
immunoprecipitation (IP)

western blot
Anti-CXCR4 antibody produced in rabbit, IgG fraction of antiserum, buffered aqueous solution,
Reattività con
human, mouse
Applicazione
ELISA
flow cytometry

immunocytochemistry

immunofluorescence

immunoprecipitation (IP)

western blot
Anti-CXCR4 Antibody, clone 12G5, clone 12G5, from mouse,
Reattività con
human
Applicazione
flow cytometry
immunocytochemistry

neutralization
Monoclonal Anti-CXCR4 antibody produced in mouse, clone 1F8, ascites fluid,
Reattività con
human
Applicazione
ELISA
western blot
Anti-CXCR4 antibody produced in chicken, affinity isolated antibody, buffered aqueous solution,
Reattività con
human, mouse, rat
Applicazione
western blot

Proteins

N° Catalogo
Descrizione
Specie
ChemiSCREEN CXCR4 Membrane Preparation, Human CXCR4 GPCR membrane preparation for Radioligand binding Assays & GTPgammaS binding.,
Specie
human

esiRNA

N° Catalogo
Descrizione
Specie
MISSION® esiRNA, targeting mouse Cxcr4,
Specie
mouse
MISSION® esiRNA, targeting human CXCR4,
Specie
human