Passa al contenuto
Merck

CDK9

cyclin-dependent kinase 9

Sinonimi:
C-2k, CDC2L4, CTK1, PITALRE, TAK
Specie:
ID UniProtKB:
ID gene:
  • Human(1025) Summary: The protein encoded by this gene is a member of the cyclin-dependent protein kinase (CDK) family. CDK family members are highly similar to the gene products of S. cerevisiae cdc28, and S. pombe cdc2, and known as important cell cycle regulators. This kinase was found to be a component of the multiprotein complex TAK/P-TEFb, which is an elongation factor for RNA polymerase II-directed transcription and functions by phosphorylating the C-terminal domain of the largest subunit of RNA polymerase II. This protein forms a complex with and is regulated by its regulatory subunit cyclin T or cyclin K. HIV-1 Tat protein was found to interact with this protein and cyclin T, which suggested a possible involvement of this protein in AIDS. [provided by RefSeq, Jul 2008]
  • Mouse(107951) cyclin-dependent kinase 9 (CDC2-related kinase)
  • Rat(362110) cyclin-dependent kinase 9
  • domestic guinea pig(100725846) cyclin-dependent kinase 9
  • naked mole-rat(101722666) cyclin-dependent kinase 9
  • sheep(101109788) cyclin-dependent kinase 9
  • Zebrafish(321602) cyclin-dependent kinase 9 (CDC2-related kinase)
  • cow(520580) cyclin-dependent kinase 9
  • dog(491325) cyclin-dependent kinase 9
  • chicken(417226) cyclin-dependent kinase 9
  • fruit fly(37586) Cyclin-dependent kinase 9
  • domestic cat(101097767) cyclin-dependent kinase 9

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Antibodies

N° Catalogo
Descrizione
Reattività con
Applicazione
Anti-CDK9 Antibody, clone 1F9 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Reattività con
human, monkey, mouse, rat
Applicazione
affinity binding assay
immunocytochemistry

immunohistochemistry

western blot
Anti-CDK9 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reattività con
human
Applicazione
immunofluorescence
immunohistochemistry
Anti-CDK9, (N-terminal) antibody produced in rabbit, affinity isolated antibody,
Reattività con
human
Applicazione
immunohistochemistry
western blot
Anti-phospho-CDK9 (pThr186) antibody produced in rabbit, affinity isolated antibody,
Reattività con
human, mouse, rat
Applicazione
ELISA
western blot
Anti-CDK9 antibody produced in rabbit, ,
Reattività con
Applicazione
immunohistochemistry
western blot

Small Molecule - Inhibitor

N° Catalogo
Descrizione
Specie
Flavopiridol, ≥98% (HPLC), powder,
Specie
human
Roscovitine, ≥98% (TLC),
Specie
human, mouse, rat
Olomoucine, ≥98% (HPLC),
Specie
human, rat

Proteins

N° Catalogo
Descrizione
Specie
Cdk9/Cyclin T1 Protein, active, 10 µg, Active, C-terminal 6His-tagged, full length recombinant, human Cdk9 co-expressed with untagged, full-length human Cyclin T1, for use in Kinase Assays.,
Specie
human
CDK9/CyclinK, active, GST tagged human, PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Specie
human

esiRNA

N° Catalogo
Descrizione
Specie
MISSION® esiRNA, targeting human CDK9,
Specie
human