CDK1
cyclin-dependent kinase 1
Sinonimi:
CDC2, CDC28A, P34CDC2
Specie:
Human CDK1 (983), Mouse Cdk1 (12534), Rat Cdk1 (54237), dog CDK1 (488997), Zebrafish cdk1 (80973), chicken CDK1 (396252), naked mole-rat Cdk1 (101717463), domestic guinea pig Cdk1 (100735946), Goat CDK1 (100861361), cow CDK1 (281061)
ID UniProtKB:
ID gene:
- Human(983) Summary: The protein encoded by this gene is a member of the Ser/Thr protein kinase family. This protein is a catalytic subunit of the highly conserved protein kinase complex known as M-phase promoting factor (MPF), which is essential for G1/S and G2/M phase transitions of eukaryotic cell cycle. Mitotic cyclins stably associate with this protein and function as regulatory subunits. The kinase activity of this protein is controlled by cyclin accumulation and destruction through the cell cycle. The phosphorylation and dephosphorylation of this protein also play important regulatory roles in cell cycle control. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009]
- Mouse(12534) cyclin-dependent kinase 1
- Rat(54237) cyclin-dependent kinase 1
- dog(488997) cyclin-dependent kinase 1
- Zebrafish(80973) cyclin-dependent kinase 1
- chicken(396252) cyclin-dependent kinase 1
- naked mole-rat(101717463) cyclin-dependent kinase 1
- domestic guinea pig(100735946) cyclin-dependent kinase 1
- Goat(100861361) cyclin-dependent kinase 1
- cow(281061) cyclin-dependent kinase 1
- sheep(100216432) cyclin-dependent kinase 1
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Antibodies
N° Catalogo
Descrizione
Reattività con
Applicazione
Anti-Phospho-CDK1-T14 antibody produced in rabbit, ,
Reattività con
human, mouse, rat
Applicazione
immunofluorescence
western blot
western blot
Anti-phospho-Cdk1 (Thr14, Tyr15)Antibody, clone CP3.2, clone CP3.2, from mouse,
Reattività con
human
Applicazione
immunocytochemistry
western blot
western blot
Anti-Phospho-CDK1-T161 antibody produced in rabbit, ,
Reattività con
human, mouse
Applicazione
immunofluorescence
immunohistochemistry
immunoprecipitation (IP)
western blot
immunohistochemistry
immunoprecipitation (IP)
western blot
Anti-phospho-CDC2 (pThr161) antibody produced in rabbit, affinity isolated antibody,
Reattività con
human, mouse, rat
Applicazione
ELISA
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-CDC2 (C-terminal) antibody produced in rabbit, affinity isolated antibody,
Reattività con
human
Applicazione
immunohistochemistry
western blot
western blot
Small Molecule - Inhibitor
Proteins
N° Catalogo
Descrizione
Specie
CDK1/CyclinB1, active, GST tagged human, PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Specie
human
CDK1/Cyclin A2, active, GST tagged human, PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Specie
human
esiRNA
N° Catalogo
Descrizione
Specie