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Merck

CASP7

caspase 7, apoptosis-related cysteine peptidase

Sinonimi:
CASP-7, CMH-1, ICE-LAP3, LICE2, MCH3
Specie:
ID UniProtKB:
ID gene:
  • Human(840) Summary: This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. The precursor of the encoded protein is cleaved by caspase 3 and 10, is activated upon cell death stimuli and induces apoptosis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, May 2012]
  • Mouse(12369) caspase 7
  • Rat(64026) caspase 7
  • Goat(100861343) caspase 7, apoptosis-related cysteine peptidase
  • dog(486896) caspase 7, apoptosis-related cysteine peptidase
  • Zebrafish(553634) caspase 7, apoptosis-related cysteine peptidase
  • chicken(423901) caspase 7, apoptosis-related cysteine peptidase
  • naked mole-rat(101709568) caspase 7, apoptosis-related cysteine peptidase
  • domestic guinea pig(100715159) caspase 7, apoptosis-related cysteine peptidase
  • cow(526279) caspase 7, apoptosis-related cysteine peptidase
  • sheep(101122741) caspase 7, apoptosis-related cysteine peptidase
  • domestic cat(768262) caspase 7, apoptosis-related cysteine peptidase

Custom & Knockdown Gene Products

ELISA

Numero di prodotto
Descrizione
Specie
Human Caspase-7 ELISA, for serum, plasma and cell culture supernatants,
Specie
human

Antibodies

Numero di prodotto
Descrizione
Reattività con
Applicazione
Anti-Caspase-7 (ab2) antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
Reattività con
human, mouse, rat
Applicazione
ELISA
immunohistochemistry

western blot
Anti-Caspase-7 Antibody, clone 1E21 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Reattività con
human
Applicazione
flow cytometry
immunohistochemistry

western blot
Monoclonal Anti-Caspase 7 antibody produced in rat, clone 11E4, purified immunoglobulin, buffered aqueous solution,
Reattività con
human
Applicazione
immunoprecipitation (IP)
microarray

western blot

Small Molecule - Inhibitor

Numero di prodotto
Descrizione
Specie
N-Acetyl-Asp-Glu-Val-Asp-al, ≥95%, powder,
Specie
human
NSCI, ≥97% (HPLC), solid,
Specie
human

esiRNA

Numero di prodotto
Descrizione
Specie
MISSION® esiRNA, targeting human CASP7,
Specie
human