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Merck

CACNA1E

calcium channel, voltage-dependent, R type, alpha 1E subunit

Sinonimi:
BII, CACH6, CACNL1A6, Cav2.3
Specie:
ID UniProtKB:
ID gene:
  • Human(777) Summary: Voltage-dependent calcium channels are multisubunit complexes consisting of alpha-1, alpha-2, beta, and delta subunits in a 1:1:1:1 ratio. These channels mediate the entry of calcium ions into excitable cells, and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. This gene encodes the alpha-1E subunit of the R-type calcium channels, which belong to the 'high-voltage activated' group that maybe involved in the modulation of firing patterns of neurons important for information processing. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Apr 2011]
  • Mouse(12290) calcium channel, voltage-dependent, R type, alpha 1E subunit
  • Rat(54234) calcium channel, voltage-dependent, R type, alpha 1E subunit
  • naked mole-rat(101701145) calcium channel, voltage-dependent, R type, alpha 1E subunit
  • domestic guinea pig(100716749) calcium channel, voltage-dependent, R type, alpha 1E subunit
  • domestic cat(101093985) calcium channel, voltage-dependent, R type, alpha 1E subunit
  • Domestic Rabbit(100009403) calcium channel, voltage-dependent, R type, alpha 1E subunit
  • sheep(101102503) calcium channel, voltage-dependent, R type, alpha 1E subunit
  • cow(353113) calcium channel, voltage-dependent, R type, alpha 1E subunit
  • chicken(424412) calcium channel, voltage-dependent, R type, alpha 1E subunit
  • Zebrafish(567702) voltage-dependent R-type calcium channel subunit alpha-1E
  • dog(490305) calcium channel, voltage-dependent, R type, alpha 1E subunit

Custom & Knockdown Gene Products

Small Molecule - Allosteric Modulator

Numero di prodotto
Descrizione
Specie
Gabapentin, United States Pharmacopeia (USP) Reference Standard,
Specie
human
Gabapentin, Pharmaceutical Secondary Standard; Certified Reference Material,
Specie
human
Gabapentin solution, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®,
Specie
human
Pregabalin, European Pharmacopoeia (EP) Reference Standard,
Specie
human
Gabapentin solution, 10 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®,
Specie
human

Antibodies

Numero di prodotto
Descrizione
Reattività con
Applicazione
Anti-CACNA1S antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reattività con
human
Applicazione
immunohistochemistry
Anti-CACNA1S antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reattività con
human
Applicazione
immunohistochemistry
Monoclonal Anti-Dihydropyridine Receptor (α1 Subunit) antibody produced in mouse, clone 1A, buffered aqueous solution,
Reattività con
guinea pig, human, mouse, rabbit, rat
Applicazione
immunohistochemistry
immunoprecipitation (IP)

western blot

Small Molecule - Blocker

Numero di prodotto
Descrizione
Specie
Amlodipine besylate, Pharmaceutical Secondary Standard; Certified Reference Material,
Specie
human
Amlodipine besylate, ≥98% (HPLC),
Specie
human
Verapamil hydrochloride, United States Pharmacopeia (USP) Reference Standard,
Specie
human
Amlodipine besylate, United States Pharmacopeia (USP) Reference Standard,
Specie
human
Verapamil hydrochloride solution, 1.0 mg/mL in methanol (as free base), ampule of 1 mL, certified reference material, Cerilliant®,
Specie
human

esiRNA

Numero di prodotto
Descrizione
Specie
MISSION® esiRNA, targeting human CACNA1E,
Specie
human
MISSION® esiRNA, targeting mouse Cacna1e,
Specie
mouse
MISSION® esiRNA, targeting human CACNA1S,
Specie
human
MISSION® esiRNA, targeting mouse Cacna1s,
Specie
mouse