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810298C

Avanti

18:1-18:1-C11 TopFluor™ TG

Avanti Research™ - A Croda Brand 810298C

Synonym(s):

1,2-dioleoyl-3-[11-(dipyrrometheneboron difluoride)undecanoyl]-sn-glycerol

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€223.00

€223.00

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1 MG
€223.00

About This Item

Empirical Formula (Hill Notation):
C63H105 BF2N2O6
CAS Number:
2260795-66-0
Molecular Weight:
1035.33
MDL number:
MFCD00066515
UNSPSC Code:
12352211
NACRES:
NA.25

€223.00

Please contact Customer Service for Availability
Request a Bulk Order

Assay

>99% (TLC)

form

liquid

packaging

pkg of 1 × 1 mL (810298C-1mg)

manufacturer/tradename

Avanti Research™ - A Croda Brand 810298C

concentration

1 mg/mL (810298C-1mg)

shipped in

dry ice

storage temp.

−20°C

General description

Lipid droplets (LDs) are organelles that store lipids as reservoirs of metabolic energy and membrane lipid precursors, and they have been identified in the nucleus of some cells. LDs can be found in most eukaryotic cells. Most prominent are LDs in adipocytes, which make up most of the cellular volume, but other metabolically active cell types, such as liver or muscle cells, also have abundant LDs. LDs are unusual organelles in that they are bound by a monolayer of surface phospholipids, into which specific proteins are embedded, such as perilipins and metabolic enzymes. The cell biology of LDs as cellular organelles is only beginning to be unraveled. Avanti now offers a series of fluorescently-labeled mono-, di-, and triglycerides, which are useful for studying these important cellular organelles.

Application

18:1-18:1-C11TopFluor™ TG (1,2-dioleoyl-3-[11-(dipyrrometheneboron difluoride)undecanoyl]-sn-glycerol) has been used as a standard to validate fluorescent lipid bands in fatty acid incorporation assay.[1] It may also be used in fluorescent lipid synthesis.[2]

Packaging

5 mL Clear Glass Sealed Ampule (810298C-1mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC
TopFluor is a trademark of Avanti Polar Lipids, LLC

Pictograms

Skull and crossbonesHealth hazard
GHS06,GHS08

Signal Word

Danger

Hazard Classifications

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3

Target Organs

Central nervous system, Liver,Kidney

WGK

WGK 3

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

EU REACH Annex XVII (Restriction List)

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Hanaa Hariri et al.
The Journal of cell biology, 218(4), 1319-1334 (2019-02-28)
Lipid droplets (LDs) serve as cytoplasmic reservoirs for energy-rich fatty acids (FAs) stored in the form of triacylglycerides (TAGs). During nutrient stress, yeast LDs cluster adjacent to the vacuole/lysosome, but how this LD accumulation is coordinated remains poorly understood. The
Øystein Sæle et al.
Biochimica et biophysica acta. Molecular and cell biology of lipids, 1863(9), 948-957 (2018-05-21)
The zebrafish larva is a powerful tool for the study of dietary triglyceride (TG) digestion and how fatty acids (FA) derived from dietary lipids are absorbed, metabolized and distributed to the body. While fluorescent FA analogues have enabled visualization of
Robert V Farese et al.
Cell, 139(5), 855-860 (2009-12-01)
Long underappreciated as important cellular organelles, lipid droplets are finally being recognized as dynamic structures with a complex and interesting biology. In light of this newfound respect, we discuss emerging views on lipid droplet biology and speculate on the major
Yuki Ohsaki et al.
The Journal of cell biology, 212(1), 29-38 (2016-01-06)
Lipid droplets (LDs) in the nucleus of hepatocyte-derived cell lines were found to be associated with premyelocytic leukemia (PML) nuclear bodies (NBs) and type I nucleoplasmic reticulum (NR) or the extension of the inner nuclear membrane. Knockdown of PML isoform
Nora Kory et al.
Trends in cell biology, 26(7), 535-546 (2016-03-21)
How proteins specifically localize to the phospholipid monolayer surface of lipid droplets (LDs) is being unraveled. We review here the major known pathways of protein targeting to LDs and suggest a classification framework based on the localization origin for the
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