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330707

Avanti

SPLASH LIPIDOMIX Mass Spec Standard

Avanti Research - A Croda Brand

Synonym(s):

SPLASH LIPIDOMIX Mass Spec Standard, Single-vial Prepared Lipidomic Analytical Standard for Human plasma lipids

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About This Item

UNSPSC Code:
41116107
NACRES:
NA.25

form

methanol solution

packaging

pkg of 1 × 1 mL (330707-1EA)

manufacturer/tradename

Avanti Research - A Croda Brand

concentration

1 mg/mL (330707-1EA)

technique(s)

mass spectrometry (MS): suitable

application(s)

lipidomics
metabolomics

shipped in

dry ice

storage temp.

−20°C

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General description

Make a splash in your lab and dive right into Lipidomics with our easy to use mixture of deuterium labeled lipids. The SPLASH LIPIDOMIX Mass Spec Standard includes all of the major lipid classes at ratios relative to human plasma, allowing one easy internal standard solution to be added to every sample. This internal standard mixture was developed in collaboration with Kim Ekroos (Zora Biosciences).

Application

SPLASH LIPIDOMIX Mass Spec Standard has been used:
  • as an internal standard for non-alcoholic fatty liver disease (NAFLD) signature analysis from mice and human samples
  • as an internal standard in the quantification of phospholipids from duodenum, liver, and adipose tissue using ultra performance liquid chromatography quadrupole-time of-flight mass spectrometry (UPLC-q-Tof MS)
  • in human cell lines prior to lipid analysis by liquid chromatography-mass spectrometry (LC-MS) analysis

Features and Benefits

  • Save time: pre-mixed internal standards.
  • Save money: 1 vial is sufficient for 100 plasma samples.
  • Exact concentrations provided for quantitative lipidomic analysis.
  • Applicable to multiple MS approaches.
  • Concentration of each lipid class optimized for plasma analysis.

Packaging

2 mL Amber Glass Sealed Ampule (330707-1EA)

Components

The SPLASH LIPIDOMIX Mass Spec Standard is supplied in 1 mL of methanol and contains the following components:

Mixture ComponentTarget Conc. (μg/mL)
  • 15:0-18:1(d7) PC160
  • 15:0-18:1(d7) PE5
  • 15:0-18:1(d7) PS5
  • 15:0-18:1(d7) PG30
  • 15:0-18:1(d7) PI10
  • 15:0-18:1(d7) PA7
  • 18:1(d7) LPC25
  • 18:1(d7) LPE5
  • 18:1(d7) Chol Ester350
  • 18:1(d7) MG2
  • 15:0-18:1(d7) DG10
  • 15:0-18:1(d7)-15:0 TG55
  • 18:1(d9) SM30
  • Cholesterol (d7)100

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC
LIPIDOMIX is a trademark of Avanti Polar Lipids, LLC
SPLASH is a trademark of Avanti Polar Lipids, LLC

Kit Components Also Available Separately

Product No.
Description
SDS

  • 791637C15:0-18:1-d7-PC, Avanti Research - A Croda Brand 160μg/mLSDS

  • 791638C15:0-18:1-d7-PE, Avanti Research - A Croda Brand 5μg/mLSDS

  • 791639C15:0-18:1-d7-PS, Avanti Research - A Croda Brand 5μg/mLSDS

  • 791640C15:0-18:1-d7-PG, Avanti Research - A Croda Brand 791640C 30μg/mLSDS

  • 791641C15:0-18:1-d7-PI, Avanti Research - A Croda Brand 10μg/mLSDS

  • 791642C15:0-18:1-d7-PA, Avanti Research - A Croda Brand 7μg/mLSDS

  • 791643C18:1-d7 Lyso PC, Avanti Research - A Croda Brand 25μg/mLSDS

  • 791644C18:1-d7 Lyso PE, Avanti Research - A Croda Brand 791644C 5μg/mLSDS

  • 791645C18:1-d7-cholesterol, Avanti Research - A Croda Brand 791645C 350μg/mLSDS

  • 791646C18:1-d7 MG, Avanti Research - A Croda Brand 791646C 2μg/mLSDS

  • 791647C15:0-18:1-d7 DG, Avanti Research - A Croda Brand 791647C 10μg/mLSDS

  • 791648C15:0-18:1-d7-15:0 TG, Avanti Research - A Croda Brand 791648C 55μg/mLSDS

  • 791649C18:1-d9 SM, Avanti Research - A Croda Brand 30μg/mLSDS

  • 700041Pcholesterol-d7, Avanti Research - A Croda Brand 100μg/mLSDS

See All (14)

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Signal Word

Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1

Target Organs

Eyes,Central nervous system

Storage Class Code

3 - Flammable liquids

WGK

WGK 2

Flash Point(F)

49.5 °F - closed cup

Flash Point(C)

9.7 °C - closed cup


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Analytical and bioanalytical chemistry, 412(10), 2375-2388 (2020-02-23)
Ultrahigh-performance supercritical fluid chromatography-mass spectrometry (UHPSFC/MS) has a great potential for the high-throughput lipidomic quantitation of biological samples; therefore, the full optimization and method validation of UHPSFC/MS is compared here with ultrahigh-performance liquid chromatography-mass spectrometry (UHPLC/MS) in hydrophilic interaction liquid
Bo Burla et al.
Journal of lipid research, 59(10), 2001-2017 (2018-08-18)
Human blood is a self-regenerating lipid-rich biological fluid that is routinely collected in hospital settings. The inventory of lipid molecules found in blood plasma (plasma lipidome) offers insights into individual metabolism and physiology in health and disease. Disturbances in the
Naren Gajenthra Kumar et al.
PloS one, 13(10), e0206606-e0206606 (2018-11-01)
Modification of the host lipidome via secreted enzymes is an integral, but often overlooked aspect of bacterial pathogenesis. In the current era of prevalent antibiotic resistance, knowledge regarding critical host pathogen lipid interactions has the potential for use in developing

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