Annals of the New York Academy of Sciences, 1125, 215-229 (2007-12-22)
The history and changing function of tungsten as the heaviest element in biological systems is given. It starts from an inhibitory element/anion, especially for the iron molybdenum-cofactor (FeMoCo)-containing enzyme nitrogenase involved in dinitrogen fixation, as well as for the many
The toxicity of nanomaterials has been well known, but mechanisms involved have been little known. This study was aimed at looking at direct interaction between nanomaterials and naked DNA for some fundamental understanding. Two different types of nanomaterials, carbon nanotubes
Synthetic analogues and reaction systems relevant to the molybdenum and tungsten oxotransferases.
Frontiers in bioscience : a journal and virtual library, 8, s813-s825 (2003-09-06)
Polyoxometalates (POM) have a rich and promising photochemical behavior. Upon illumination at the O M CT band (i.e., in UV and near-visible area) become powerful oxidizing reagents able to oxidize various organic compounds. In the process POM undergo stepwise reduction
The molybdenum enzymes 4-hydroxybenzoyl-CoA reductase and pyrogallol-phloroglucinol transhydroxylase and the tungsten enzyme acetylene hydratase catalyze reductive dehydroxylation reactions, i.e., transhydroxylation between phenolic residues and the addition of water to a triple bond. Such activities are unusual for this class of
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