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Key Documents

MAB5296

Sigma-Aldrich

Anti-Oxytocin Antibody, clone 4G11

ascites fluid, clone 4G11, Chemicon®

Synonym(s):

Anti-OT, Anti-OT-NPI, Anti-OXT-NPI

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About This Item

UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41

biological source

mouse

Quality Level

100

antibody form

ascites fluid

antibody product type

primary antibodies

clone

4G11, monoclonal

species reactivity

rat, human

manufacturer/tradename

Chemicon®

technique(s)

ELISA: suitable
immunohistochemistry: suitable

isotype

IgG1

NCBI accession no.

NM_000915.2

UniProt accession no.

P01178

shipped in

dry ice

target post-translational modification

unmodified

Gene Information

human ... OXTR(5021)

Specificity

Recognizes Oxytocin. No reactivity to arginine vasopressin, vasotocin or [Asu1,6,Arg8]-vasopressin by competitive ELISA.

Immunogen

Oxytocin conjugated to thyroglobulin.

Application

Immunohistochemistry on 4% paraformaldehyde fixed frozen tissue: 1:5,000-1:10,000.

ELISA: 1:1,000,000

Optimal working dilutions must be determined by the end user.
This Anti-Oxytocin Antibody, clone 4G11 is validated for use in ELISA, IH for the detection of Oxytocin.

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

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Storage Class Code

12 - Non Combustible Liquids

WGK

nwg

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Mamoru Tanida et al.
Diabetes, 64(11), 3725-3736 (2015-08-28)
Nesfatin-1 acts on the hypothalamus and regulates the autonomic nervous system. However, the hypothalamic mechanisms of nesfatin-1 on the autonomic nervous system are not well understood. In this study, we found that intracerebroventricular (ICV) administration of nesfatin-1 increased the extracellular
Amy S Kohtz et al.
Psychopharmacology, 235(7), 2051-2063 (2018-04-20)
Initial drug abstinence (modeled here as Extinction Day 1, ED1) is a critical time point in the progression of addiction that is strongly influenced by stress and sex. ED1 induces corticosterone release in both sexes, and cocaine-seeking during ED1 can
Ranjan K Roy et al.
Communications biology, 1, 160-160 (2018-10-16)
Myocardial infarction (MI) initiates an increase in cardiac sympathetic nerve activity (SNA) that facilitates potentially fatal arrhythmias. The mechanism(s) underpinning sympathetic activation remain unclear. Some neuronal populations within the hypothalamic paraventricular nucleus (PVN) have been implicated in SNA. This study
Christina N Rogers et al.
American journal of primatology, 80(10), e22875-e22875 (2018-05-26)
Oxytocin (OT) and arginine-vasopressin (AVP) are involved in the regulation of complex social behaviors across a wide range of taxa. Despite this, little is known about the neuroanatomy of the OT and AVP systems in most non-human primates, and less
Yuko Maejima et al.
Scientific reports, 9(1), 18360-18360 (2019-12-05)
Body weight (BW) is regulated in age-dependent manner; it continues to increase during growth period, and reaches a plateau once reaching adulthood. However, its underlying mechanism remains unknown. Regarding such mechanisms in the brain, we here report that neural circuits from
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