113727
Norphenylephrine hydrochloride
98%
Synonym(s):
α-Aminomethyl-3-hydroxybenzyl alcohol hydrochloride, 3,α-Dihydroxyphenethylamine hydrochloride, Norfenefrine hydrochloride
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About This Item
Linear Formula:
HOC6H4CH(CH2NH2)OH · HCl
CAS Number:
Molecular Weight:
189.64
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22
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Quality Level
Assay
98%
form
solid
mp
162-164 °C (lit.)
functional group
amine
hydroxyl
SMILES string
Cl.NCC(O)c1cccc(O)c1
InChI
1S/C8H11NO2.ClH/c9-5-8(11)6-2-1-3-7(10)4-6;/h1-4,8,10-11H,5,9H2;1H
InChI key
OWMFSWZUAWKDRR-UHFFFAOYSA-N
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Related Categories
Application
Norphenylephrine hydrochloride was used in the study of the effects of phenylephrine on the isolated heart of rabbit[1].
Signal Word
Warning
Hazard Statements
Hazard Classifications
Acute Tox. 4 Oral
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
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P J Fletcher et al.
British journal of pharmacology, 97(2), 483-489 (1989-06-01)
1. The effects on food intake in rats of injection of m- and p-octopamine into the paraventricular nucleus (PVN) of the hypothalamus were examined, and compared to the effects of noradrenaline (NA). 2. m-Octopamine injected into the PVN induced a
B G Benfey
British journal of pharmacology, 48(1), 132-138 (1973-05-01)
1. In the driven rabbit left atrium alpha-adrenoceptors mediate the inotropic effect of phenylephrine and the prolongation of functional refractory period by sympathomimetic amines.2. These receptors are highly sensitive to blockade by phentolamine and phenoxybenzamine.3. Prolongation of functional refractory period
H G Zimmer
Journal of molecular medicine (Berlin, Germany), 75(11-12), 849-859 (1998-01-15)
The effect of beta- and alpha-adrenergic stimulation on cardiovascular function and development of cardiac hypertrophy was studied in rats by measuring the heart weight/body weight and cardiac RNA/DNA ratios. Beta-receptor stimulation with isoproterenol over 3 days induced an increase in
Yan Gao et al.
Electrophoresis, 29(9), 1918-1923 (2008-04-04)
This study presents a four-channel electrophoresis chip platform, featuring double-cross hydrostatic sample injection, for rapid chiral selector screening. This platform needs only five electrodes to drive microchip electrophoresis in four separate channels for screening four chiral selectors at a time.
M Maeda et al.
International journal of radiation applications and instrumentation. Part A, Applied radiation and isotopes, 41(5), 463-469 (1990-01-01)
[11C]-p- and m-octopamine hydrochloride were synthesized from [11C]HCN in a two-step sequence. Chemical and enzymatic approaches were used for the formation of the [11C]cyanohydrin intermediates as the key step. Isolated radiochemical yields of 0.7-2.3% at the end-of-synthesis were obtained with
Chromatograms
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