B7901

Boric acid

suitable for electrophoresis, ≥99.5%

• Linear Formula: H₃BO₃
• CAS Number: 10043-35-3
• Molecular Weight: 61.83
• EC Number: 233-139-2
• MDL number: MFCD00011337
• UNSPSC Code: 12161700
• eCl@ss: 38120104
• PubChem Substance ID: 24892029
• NACRES: NA.25

Properties

• vapor pressure: 2.6 mmHg ( 20 °C)
• Assay: ≥99.5%
• form: powder
• technique(s): electrophoresis: suitable
• impurities: ≤0.005% Insoluble in methanol
• pH: 8.2-10.1
• mp: 160 °C (dec.) (lit.)
• solubility: H₂O: 40 mg/mL, clear, colorless
• density: 1.43 g/cm³ at 20 °C
• anion traces: chloride (Cl^-): ≤0.001%; phosphate (PO₄^3-): ≤0.001%; sulfate (SO₄^2-): ≤0.01%
• cation traces: Ca: ≤0.005%; Fe: ≤0.001%; heavy metals (as Pb): ≤0.001%
• suitability: suitable for electrophoresis (as a reagent)
• storage temp.: room temp
• SMILES string: OB(O)O
• InChI: 1S/BH3O3/c2-1(3)4/h2-4H
• InChI key: KGBXLFKZBHKPEV-UHFFFAOYSA-N

Description

General description

Boric acid is a weak acid and is widely used in multi-purpose solutions (MPS) as a buffering agent. It is less toxic and non-volatile in nature.

Application

Boric acid has been used as a component of tris borate buffer:

• for native polyacrylamide gel electrophoresis (PAGE) and denaturing urea-PAGE of tRNA samples(80)
• for urea-polyacrylamide electrophoresis of RNA samples(81)
• for agarose gel electrophoresis of DNA samples(82)

Biochem/physiol Actions

Boric acid is used in the periodontal therapy as an irrigation solution as it elicits bactericidal effects in microbial biofilms in root canal. Boric acid may favor osteoblastic activity and inhibit bone loss. It inhibits Candida albicans fungal infection and has potential to treat vaginal infection.

Safety Information

• Pictograms: GHS08
• Signal Word: Danger
• Hazard Statements: H360FD
• Precautionary Statements: P201 - P202 - P280 - P308 + P313 - P405 - P501
• Hazard Classifications: Repr. 1B
• Storage Class Code: 6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects
• WGK: WGK 1
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves