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U5128

Sigma-Aldrich

Urea

ACS reagent, 99.0-100.5%

Synonym(s):

Carbamide, Carbonyldiamide

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5 G
₹3,279.98
100 G
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₹6,790.00
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5 G
₹3,279.98
100 G
₹3,430.00
500 G
₹6,210.00
1 KG
₹6,790.00
5 KG
₹15,780.00

About This Item

Linear Formula:
NH2CONH2
CAS Number:
Molecular Weight:
60.06
Beilstein:
635724
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.21
form:
solid
Assay:
≤0.001% (Heavy Metals by ICP-OES, metals basis)
99.0-100.5%

₹3,279.98


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grade

ACS reagent

Quality Level

Assay

≤0.001% (Heavy Metals by ICP-OES, metals basis)
99.0-100.5%

form

solid

impurities

≤0.01% Insoluble matter

ign. residue

≤0.01%

mp

132-135 °C (lit.)

solubility

H2O: soluble 480 g/L at 20 °C

density

1.335 g/mL at 25 °C (lit.)

anion traces

chloride (Cl-): ≤5 ppm
sulfate (SO42-): ≤0.001%

cation traces

Fe: ≤0.001%

functional group

amine

SMILES string

NC(N)=O

InChI

1S/CH4N2O/c2-1(3)4/h(H4,2,3,4)

InChI key

XSQUKJJJFZCRTK-UHFFFAOYSA-N

Gene Information

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General description

Urea is a colourless organic compound, without any odour. It is easily soluble in water.[1]

Application

Urea has been used:
  • to adjust the urea nitrogen concentration to a preferred range in blood reservoir for evaluating the dialyzer urea clearance[2]
  • to prepare standards to measure urea synthesis[3]
  • to prepare standards for blood urea nitrogen assay[4]

Used for the denaturation of proteins and as a mild solubilization agent for insoluble or denatured proteins. Useful for renaturing proteins from samples already denatured with 6 M guanidine chloride such as inclusion bodies. May be used with guanidine hydrochloride and dithiothreitrol (DTT) in the refolding of denatured proteins into their native or active form.

Biochem/physiol Actions

Urea participates in the metabolism of nitrogenous substances. It serves as a nitrogen source, when used in fertilizers. Urea is used in manufacturing chemical compounds.[1] It is widely used in the agricultural industry as a fertilizer as well as an animal feed additive, which is used as a nitrogen supplement in animal husbandry.[5] Urea has adverse effects on seed germination, seedling growth and early plant growth in soil.[6]

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Slide 1 of 3

1 of 3

Urea: Synthesis, Properties and Uses (2012)
Elimination of the adverse effects of urea fertilizer on seed germination, seedling growth, and early plant growth in soil
Bremner JM and Krogmeier MJ
Proceedings of the National Academy of Sciences of the USA, 85(13), 4601-4604 (1988)
Hepatic targeting and biodistribution of human fetal liver stem/progenitor cells and adult hepatocytes in mice
Cheng K, et al.
Hepatology, 50(4), 1194-1203 (2009)
Hemodialyzer mass transfer-area coefficients for urea increase at high dialysate flow rates
Leypoldt JK, et al.
Kidney International, 51(6), 2013-2017 (1997)
CHAPTER 16 - METHODS OF FEEDING UREA TO LIVESTOCK
Urea As a Protein Supplement, 321-327 (1967)

Articles

A shortened review of fundamentals of Porous Graphitic Carbon (PGC) materials. What they are and how do they work as a stationary phase material in HPLC?.

Questions

1–2 of 2 Questions  
  1. How can I determine the shelf life / expiration / retest date of this product?

    1 answer
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

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  2. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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