NIST914B

Creatinine

NIST^® SRM^® 914b

• Synonym(s): 2-Amino-1-methyl-2-imidazolin-4-one, 2-Imino-1-methylimidazolidin-4-one, 2-Imino-N-methylhydantoin
• Empirical Formula (Hill Notation): C₄H₇N₃O
• CAS Number: 60-27-5
• Molecular Weight: 113.12
• Beilstein: 112061
• MDL number: MFCD00059730
• UNSPSC Code: 41116107
• NACRES: NA.24

Properties

• grade: certified reference material
• packaging: pkg of 10 g
• manufacturer/tradename: NIST^®
• technique(s): NMR: suitable
• mp: 295 °C (dec.) (lit.)
• application(s): clinical testing
• format: neat
• SMILES string: CN1CC(=O)N=C1N
• InChI: 1S/C4H7N3O/c1-7-2-3(8)6-4(7)5/h2H2,1H3,(H2,5,6,8)
• InChI key: DDRJAANPRJIHGJ-UHFFFAOYSA-N

Description

General description

This Standard Reference Material (SRM) is certified as a chemical of known purity. It is intended primarily for use in the calibration and standardization of procedures used for determination of creatinine concentration and for routine evaluations of daily working standards used in these procedures. For more information, please refer to the SDS and COA.

SRM 914B_cert

SRM 914B_SDS

Application

• Creatinine assay kit: A study utilized serum creatinine-cystatin C based screening to assess sarcopenia in older adults, demonstrating the utility of creatinine assay kits in geriatric health assessments (Matsuzawa et al., 2024).


• High-purity creatinine for biochemical studies: Research on machine learning models for predicting healthcare-associated infections utilized creatinine levels as a predictor, emphasizing the need for high-purity creatinine in developing analytical tools (Wang et al., 2024).


• Creatinine analytical standard: Studies have explored the relationship between structural characteristics of medical practices and socioeconomic status of patients, where creatinine measurement played a key role in diabetes-related performance indicators, highlighting its use as an analytical standard in healthcare research (Jargalsaikhan et al., 2024).


• Creatinine metabolism research: The development of lateral flow devices for urinary biomarkers to assess kidney health incorporated creatinine analysis, showing its significance in nephrology and diagnostic research (D Souza et al., 2024).


• Creatinine for cell culture: A study on population pharmacokinetics in pediatric patients used creatinine levels to compare drug metabolism between oncology and non-oncology patients, reflecting its crucial role in clinical pharmacology and cell culture studies (Abou-Auda et al., 2024).

Other Notes

Certified for the analytes listed below.
Creatinine

See certificate for values and more details at nist.gov/SRM.

Legal Information

NIST is a registered trademark of National Institute of Standards and Technology

SRM is a registered trademark of National Institute of Standards and Technology

Safety Information

• Storage Class Code: 13 - Non Combustible Solids
• WGK: WGK 3
• Flash Point(F): 554.0 °F - closed cup
• Flash Point(C): 290 °C - closed cup