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SML1970

Sigma-Aldrich

PKUMDL-WQ-2101

≥98% (HPLC)

Synonym(s):

2,4-Dihydroxy-benzoic acid 2-[(2-hydroxy-5-nitrophenyl)methylene]hydrazide

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5 MG
₪534.00
25 MG
₪2,148.00

₪534.00


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5 MG
₪534.00
25 MG
₪2,148.00

About This Item

Empirical Formula (Hill Notation):
C14H11N3O6
CAS Number:
Molecular Weight:
317.25
UNSPSC Code:
12352200
NACRES:
NA.77

₪534.00


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Quality Level

Assay

≥98% (HPLC)

form

powder

color

light yellow to dark orange

solubility

DMSO: 2 mg/mL, clear

storage temp.

2-8°C

Compare Similar Items

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Show Differences

1 of 4

This Item
SML1965SML0730P0052
PCNA-I1 ≥98% (HPLC)

SML0730

PCNA-I1

PNU-74654 ≥98% (HPLC), solid

P0052

PNU-74654

form

powder

form

powder

form

powder

form

solid

Quality Level

100

Quality Level

-

Quality Level

100

Quality Level

100

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

2-8°C

solubility

DMSO: 2 mg/mL, clear

solubility

DMSO: 15 mg/mL, clear

solubility

DMSO: 10 mg/mL, clear

solubility

DMSO: >10 mg/mL

color

light yellow to dark orange

color

white to brown

color

white to beige

color

white to off-white

Biochem/physiol Actions

PKUMDL-WQ-2101 is a potent and selective non-NAD+-competing allosteric inhibitor of phosphoglycerate dehydrogenase (PHGDH) that selectively inhibits serine synthesis in cancer cells. PKUMDL-WQ-2101 binds to allosteric site I, which is located close to active site. PKUMDL-WQ-2101 inhibits tumor growth of MDA-MB-468 xenografts in mice.
Potent and selective non-NAD+-competing allosteric inhibitor of phosphoglycerate dehydrogenase (PHGDH)

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


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