SML0763
SC144 hydrochloride
≥98% (HPLC)
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Synonym(s):
2-(7-Fluoropyrrolo[1,2-a]quinoxalin-4-yl)hydrazide-2-pyrazinecarboxylic acid hydrochloride
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| Size/SKU | Availability | Price |
|---|---|---|
5 mg | Please contact Customer Service for Availability | ₪608.00 |
25 mg | Please contact Customer Service for Availability | ₪2,586.00 |
About This Item
Quality Segment
assay
≥98% (HPLC)
form
powder
storage condition
desiccated
color
white to light brown
solubility
DMSO: 5 mg/mL, clear (warmed)
storage temp.
−20°C
SMILES string
Fc1cc2c(cc1)[n]3c(ccc3)C(=NNC(=O)c4nccnc4)N2.Cl
InChI
1S/C16H11FN6O.ClH/c17-10-3-4-13-11(8-10)20-15(14-2-1-7-23(13)14)21-22-16(24)12-9-18-5-6-19-12;/h1-9H,(H,20,21)(H,22,24);1H
InChI key
LKFGGXYXFIICED-UHFFFAOYSA-N
Application
- as a glycoprotein 130 (gp130) inhibitor to evaluate the effect of bazedoxifene on interleukin (IL-6) mediated cell viability in pancreatic cancer cells
- as a gp130 inhibitor to study its effects on signal transducer and activator of transcription 3 (STAT3) activation in mesenchymal precursor cells (KMM) cells
- as an interleukin 6 signal transducer (IL-6ST) inhibitor in media to test its ability to block serum-induced migration/invasion
Biochem/physiol Actions
1 of 1
This Item | |||
|---|---|---|---|
| description ≥98% (HPLC) | description ≥98% (HPLC) | description ≥98% (HPLC) | description ≥98% (HPLC) |
| assay ≥98% (HPLC) | assay ≥98% (HPLC) | assay ≥98% (HPLC) | assay ≥98% (HPLC) |
| form powder | form powder | form powder | form powder |
| Quality Level 100 | Quality Level 100 | Quality Level - | Quality Level 100 |
| storage temp. −20°C | storage temp. 2-8°C | storage temp. 2-8°C | storage temp. 2-8°C |
| storage condition desiccated | storage condition desiccated | storage condition desiccated | storage condition - |
| solubility DMSO: 5 mg/mL, clear (warmed) | solubility DMSO: 10 mg/mL, clear | solubility DMSO: 2 mg/mL, clear | solubility DMSO: 10 mg/mL, clear |
Storage Class
11 - Combustible Solids
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
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