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481181

Sigma-Aldrich

Silver(I) sulfadiazine

98%

Synonym(s):

Silver sulfadiazine, Sulfadiazine silver

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₪333.00
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₪1,171.00

₪333.00


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5 G
₪333.00
25 G
₪1,171.00

About This Item

Empirical Formula (Hill Notation):
C10H9AgN4O2S
CAS Number:
Molecular Weight:
357.14
EC Number:
MDL number:
UNSPSC Code:
12352302
PubChem Substance ID:
NACRES:
NA.23
form:
powder

₪333.00


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Quality Level

Assay

98%

form

powder

mp

285 °C (dec.) (lit.)

SMILES string

Nc1ccc(cc1)S(=O)(=O)N([Ag])c2ncccn2

InChI

1S/C10H9N4O2S.Ag/c11-8-2-4-9(5-3-8)17(15,16)14-10-12-6-1-7-13-10;/h1-7H,11H2;/q-1;+1

InChI key

UEJSSZHHYBHCEL-UHFFFAOYSA-N

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Application

Silver(I) sulfadiazine (AgSD) is popularly used for treating second-degree burn wounds as it acts as an antimicrobial agent and prevents infections.[1][2][3] Silver sulfadiazine-impregnated polyurethane (PU) foam,[4] chitosan/chondroitin sulfate films[5] may be used for wound dressing.

Storage Class Code

11 - Combustible Solids

WGK

WGK 2


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Silver sulfadiazine loaded chitosan/chondroitin sulfate films for a potential wound dressing application
Fajardo AR, et al.
Materials Science & Engineering. C, Materials For Biological Applications, 33(2), 588-595 (2013)
Steven L Percival et al.
Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society, 20(5), 647-657 (2012-09-19)
Both chronic and acute dermal wounds are susceptible to infection due to sterile loss of the innate barrier function of the skin and dermal appendages, facilitating the development of microbial communities, referred to as biofilms, within the wound environment. Microbial
[Modern possibilities of the local treatment of children with burn wounds].
L I Budkevich et al.
Khirurgiia, (10)(10), 48-51 (2012-12-14)
Vincenzina Monzillo et al.
The new microbiologica, 35(2), 175-182 (2012-06-19)
The aim of this study was to compare the in vitro activity and the impact on bacterial adhesion of two different catheters, one impregnated with chlorhexidine-silver sulfadiazine (C-SS) and the other not impregnated with antibacterial agents. The antimicrobial coating prevented
Chia-Yu Chu et al.
PloS one, 7(6), e38360-e38360 (2012-06-14)
Silver nanoparticles supported on nanoscale silicate platelets (AgNP/NSP) possess interesting properties, including a large surface area and high biocide effectiveness. The nanohybrid of AgNP/NSP at a weight ratio 7/93 contains 5-nm Ag particles supported on the surface of platelets with

Articles

Plasmonic nanoparticles have unique optical properties that can be tailored to suit a variety of applications in the biotechnology1–8 and electronics9–16 industries.

Questions

1–3 of 3 Questions  
  1. What can Silver sulfadiazine, Product 481181, be used for?

    1 answer
    1. Although silver sulfadiazine has some potential medical applications, including antibacterial actions and treatment of second and third-degree burns, this product as it is sold is not intended for use with or on humans. Product 481181 is meant for use in research and development purposes only.

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  2. What is the Department of Transportation shipping information for this product?

    1 answer
    1. Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product.

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  3. How can Silver sulfadiazine, Product 481181, be dissolved?

    1 answer
    1. Although Sigma-Aldrich does not test the solubility of the silver salt, per the chemicals encyclopedia published by the Royal Society of Chemistry (13th ed.), sulfadiazine is sparingly soluble in water (13mg/100mL at pH 5.5 and 200mg/100mL at pH 7.5), alcohol, and acetone and freely soluble in dilute mineral acids , solutions of potassium and sodium hydroxide, and aqueous ammonium hydroxide.

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