SCJ4600056
CF™ 680R aminooxy
suitable for fluorescence
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About This Item
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form
solid
Quality Level
ε (extinction coefficient)
140000 at 680 nm
absorbance ratio
A280/680 nm 0.32
fluorescence
λex 680 or 685 nm (Flow cytometry laser line)
λex 680 or 685 nm (Microscopy laser line)
λex 680 nm; λem 701 nm
suitability
suitable for fluorescence
storage temp.
−20°C
General description
CF™680 and CF™680R are two outstanding near-IR dyes excitable at about 680 nm with emission at about 700 nm. The two dyes each have unique properties suitable for different application needs. CF™680R is a novel rhodamine-based dye. The dye is highly fluorescent and, more importantly, extremely photostable. Rhodamine dyes are traditionally known to be bright and photostable. However, it has been a synthetic challenge to make functional rhodamine dyes with long wavelengths and high water solubility necessary for bio-labeling. Scientists at Biotium have overcome the challenge and invented a new way to make highly water soluble, bright and photostable rhodamine dyes with wavelengths ranging from red to near-IR. These dyes are excellent for labeling proteins, nucleic acids and small bio-molecules. They are ideal for confocal microscopy, single molecule-based imaging and other applications that demand both brightness and photostability.
Features and Benefits
1. The most photostable 680 nm dye. 2. Suitable for labeling nucleic acids and small bio-molecules. 3. Highly water-solbule and pH-insensitive.
Preparation Note
Protect from light
Legal Information
This product is distributed by Sigma-Aldrich Co. under the authorization of Biotium, Inc. This product is covered by one or more US patents and corresponding patent claims outside the US patents or pending applications owned or licensed by Biotium, Inc. including without limitation: 12/334,387; 12/607,915; 12/699,778; 12/850,578; 61/454,484. In consideration of the purchase price paid by the buyer, the buyer is hereby granted a limited, non-exclusive, non-transferable license to use only the purchased amount of the product solely for the buyer′s own internal research in a manner consistent with the accompanying product literature. Except as expressly granted herein, the sale of this product does not grant to or convey upon the buyer any license, expressly, by implication or estoppel, under any patent right or other intellectual property right of Biotium, Inc. Buyer shall not resell or transfer this product to any third party, or use the product for any commercial purposes, including without limitation, any diagnostic, therapeutic or prophylactic uses. This product is for research use only. Any other uses, including diagnostic uses, require a separate license from Biotium, Inc. For information on purchasing a license to use this product for purposes other than research, contact Biotium, Inc., 3159 Corporate Place, Hayward, CA 94545, Tel: (510) 265-1027. Fax: (510) 265-1352. Email: btinfo@biotium.com.
CF is a trademark of Biotium, Inc.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Certificates of Analysis (COA)
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Journal of neuroinflammation, 17(1), 281-281 (2020-09-24)
Increased extracellular histones in the bloodstream are known as a biomarker for vascular dysfunction associated with severe trauma or sepsis. There is limited information regarding the pathogenic role of circulating histones in neuroinflammation and cerebrovascular endothelial injury. Particularly, it remains
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