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D0761

Sigma-Aldrich

Diacetoxyscirpenol

from Fusarium sambucinum

Synonym(s):

12,13-Epoxytrichothec-9-ene-3,4,15-triol-4,15-diacetate, 4β,15-Diacetoxy-3α-hydroxy-12,13 epoxy-trichothec-9-ene, Anguidin

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About This Item

Empirical Formula (Hill Notation):
C19H26O7
CAS Number:
2270-40-8
Molecular Weight:
366.41
Beilstein:
1354986
EC Number:
218-873-3
MDL number:
MFCD00866334
UNSPSC Code:
12352200
PubChem Substance ID:
24893292

biological source

Fusarium sambucinum

storage temp.

2-8°C

SMILES string

CC(=O)OC[C@]12CCC(C)=C[C@H]1O[C@@H]3[C@H](O)[C@@H](OC(C)=O)[C@@]2(C)[C@@]34CO4

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Pictograms

Skull and crossbones
GHS06

Signal Word

Danger

Hazard Classifications

Acute Tox. 2 Oral - Eye Irrit. 2 - Skin Irrit. 2

Storage Class Code

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
092M4030V
14120406
079K4040
068K4145
067K4092

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D-Y Zhang et al.
In vitro cellular & developmental biology. Animal, 42(1-2), 27-32 (2006-04-19)
The pleiotropic drug resistance 5 gene (pdr5) encodes a multidrug membrane transporter and plays a very important role in the efflux of a broad range of chemicals in yeast cells. To study the possible function of pdr5 in insect cells
D Sklan et al.
British poultry science, 44(1), 46-52 (2003-05-10)
1. The effects of feeding T-2 toxin or diacetoxyscirpenol (DAS) at levels up to 1 ppm for 32 d on performance, health, small intestinal physiology and immune response to enteral and parenteral immunisation were examined in young poults. 2. Slight
J Perkowski et al.
Food additives and contaminants, 19(5), 478-482 (2002-05-25)
Ninety-nine naturally contaminated oat grain samples were collected in 12 plant breeding stations in different parts of Poland. T-2 toxin, HT-2 toxin and diacetoxyscirpenol (DAS) levels were determined by gas chromatography with mass selective detection (GC-MS). HT-2 was the major
Ocki Yoo et al.
Medical mycology, 44(1), 79-85 (2006-06-30)
Cordyceps contains many health-promoting constituents. Recent studies revealed that the fruiting body of cordyceps significantly alleviates hyperglycemia which usually accompanies diabetes mellitus. The mechanism of the anti-hyperglycemic effect by cordyceps, however, is not fully understood. In this study, methanolic extracts
Thanakarn Nasri et al.
Toxicology in vitro : an international journal published in association with BIBRA, 20(6), 832-840 (2006-02-14)
Several studies have shown that the mycotoxins T-2 toxin, diacetoxyscirpenol (DAS), deoxynivalenol (DON) and nivalenol (NIV) affect lymphocyte functioning. However, the molecular mechanisms underlying the immunomodulatory effects of these trichothecenes are not defined yet. In this study, the potency of
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