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04434

Sigma-Aldrich

Sodium hypophosphite

puriss., meets analytical specification of BPC63, anhydrous, 98-101%

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About This Item

Linear Formula:
NaPH2O2
CAS Number:
Molecular Weight:
87.98
EC Number:
MDL number:
UNSPSC Code:
12352302
eCl@ss:
38070302
PubChem Substance ID:
NACRES:
NA.21

grade

puriss.

Assay

98-101%

form

powder or crystals

quality

meets analytical specification of BPC63

impurities

≤0.001% heavy metals (as Pb)
≤0.2% free alkali (as CaO)

loss

≤1% loss on drying, 105 °C, 2 h

solubility

water: soluble 909 g/L at 30 °C

density

1.77 g/cm3 at 20 °C

anion traces

chloride (Cl-): ≤200 mg/kg
sulfate (SO42-): ≤200 mg/kg

cation traces

As: ≤2 mg/kg
Fe: ≤10 mg/kg

SMILES string

[Na+].[O-][PH2]=O

InChI

1S/Na.H3O2P/c;1-3-2/h;3H2,(H,1,2)/q+1;/p-1

InChI key

SIGUVTURIMRFDD-UHFFFAOYSA-M

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General description

Sodium hypophosphite, also known as sodium phosphinate, is a sodium salt of hypophosphorous acid. It is used as a reducing agent for the reduction of metal salts to metals in an aqueous solution. It is also employed as a source of hydrogen in heterogeneous catalytic transfer reductions.

Application


  • Synthesis and characterization of chitosan-copper nanocomposites and their catalytic properties for 4-nitrophenol reduction.: This study explores the synthesis of chitosan-copper nanocomposites using sodium hypophosphite as a reducing agent. The resulting nanocomposites are characterized and their catalytic properties for the reduction of 4-nitrophenol are evaluated, demonstrating the utility of sodium hypophosphite in catalytic applications (Pang et al., 2024).

  • The Durable Chitosan Functionalization of Cellulosic Fabrics.: This research focuses on the durable functionalization of cellulosic fabrics with chitosan using sodium hypophosphite as a cross-linking agent. The study highlights the improved properties of the fabrics, showcasing sodium hypophosphite′s role in textile enhancement (Flinčec Grgac et al., 2023).

  • Hypophosphite cross-linked starch succinate/chitosan membranes as alternative for packaging and pharmaceutical application.: The study investigates the development of starch succinate/chitosan membranes cross-linked with sodium hypophosphite, proposing these materials as potential alternatives for packaging and pharmaceutical applications (Bajer, 2023).

  • Tensile Strength Improvements of Ramie Fiber Threads through Combination of Citric Acid and Sodium Hypophosphite Cross-Linking.: This research improves the tensile strength of ramie fiber threads by combining citric acid and sodium hypophosphite for cross-linking, demonstrating significant enhancements in fiber properties for industrial applications (Wulandari et al., 2023).

  • Nickel-Catalyzed Sodium Hypophosphite-Participated Direct Hydrophosphonylation of Alkyne toward H-Phosphinates.: This study demonstrates a novel nickel-catalyzed hydrophosphonylation of alkynes using sodium hypophosphite. The research showcases the efficiency of sodium hypophosphite in producing H-phosphinates, highlighting its significance in chemical synthesis (Qian et al., 2023).

Storage Class Code

13 - Non Combustible Solids

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Reduction of carbon-carbon double bonds and hydrogenolysis by sodium hypophosphite.
Sala R, et al.
Tetrahedron Letters, 25(40), 4565-4568 (1984)
Rapid synthesis of copper nanoparticles by sodium hypophosphite reduction in ethylene glycol under microwave irradiation.
Zhu H-T, et al.
Journal of Crystal Growth, 270(3), 722-728 (2004)
Mohammad H Eskandari et al.
Food science & nutrition, 1(5), 392-401 (2014-05-08)
Nitrite-free and low-nitrite meat-curing systems were developed to eliminate or reduce nitrite in frankfurter-type sausages. Different composite meat-curing mixtures were formulated using cochineal and paprika as natural colorants, sodium hypophosphite (SHP) as antimicrobial agent, butylated hydroxyanisole (BHA) as antioxidant and
W S Price et al.
Biophysical chemistry, 33(3), 205-215 (1989-07-01)
A 31P-NMR method, which complements earlier 13C-NMR procedures for probing the intra-erythrocyte microenvironment, is described. Hypophosphite is an almost unique probe of the erythrocyte microenvironment, since it is rapidly transported into the cell via the band 3 protein, and intra-
Lukas J Goossen et al.
Chemical communications (Cambridge, England), (8)(8), 836-837 (2002-07-19)
A catalyst generated in situ from palladium acetate and tricyclohexylphosphine efficiently catalyzes the reduction of carboxylic acids with sodium hypophosphite in the presence of pivalic anhydride to give aldehydes with high selectivity. The low cost and convenient handling of the

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