SAB5202074

Monoclonal Anti-beta 4 Spectrin-R-Phycoerythrin antibody produced in mouse

clone S393-2, affinity isolated antibody, buffered aqueous solution

• Sinónimos: Anti-SPTBN4
• Código UNSPSC: 12352203
• NACRES: NA.45

Propiedades

• origen biológico: mouse
• conjugado: phycoerythrin (R-PE) conjugate
• forma del anticuerpo: affinity isolated antibody
• tipo de anticuerpo: primary antibodies
• clon: S393-2; monoclonal
• descripción: clone S393-2, purified immunoglobulin, buffered aqueous solution; target molecular weight: 200 kDa
• Formulario: buffered aqueous solution
• reactividad de especies: mouse (Predicted), African green monkey (Tested), rat (Predicted), human (Tested)
• envase: pkg of 100 μg
• condiciones de almacenamiento: avoid repeated freeze/thaw cycles; protect from light
• concentración: 1.0 mg/mL
• técnicas: immunofluorescence: 1:100; western blot: 1:1000
• isotipo: IgG1
• Nº de acceso UniProt: Q9H254
• Condiciones de envío: wet ice
• modificación del objetivo postraduccional: unmodified
• Información sobre el gen: human ... SPTBN4(57731)

Descripción

Inmunógeno

Immunogen Description: Fusion protein amino acids 1621-1832 (C-terminal repeats 14 to 15) of human Beta4-spectrin

Immunogen Region: C-terminal

Immunogen Species: Human

Immunogen type: Fusion protein

Aplicación

Western blotting
Dilution 1:1000
Tissue/Cell Type Used: monkey COS-Beta-4-Spectrin-His

Immunofluorescence
Dilution 1:100
Tissue/Cell Type Used: SK-N-BE

Forma física

50% glycerol, 0.1% sodium azide

PBS pH 7.4

Nota de preparación

Derived from animal serum

Almacenamiento y estabilidad

Protect from light; avoid repeated freeze-thaw cycles. Store at -20 °C long-term, 2-8 °C short-term.

Otras notas

Additional Product Details:
Does not cross react with other Beta-spectrins
Lot Expiration/Retest Date: Expires 1 year from purchase

Target/Gene Description: Spectrin is the major constituent of the cytoskeletal network underlying the erthrocyte plasma membrane and determines cell shape, arrangement of transmembrane proteins and organization of organelles. It is expressed at very low levels in many tissues, with the strongest expression in the cerebellum, spinal cord, stomach, pituitary gland, liver, pancreas, salivary gland, kidney, bladder and heart . Spectrin beta 4 is a non-erythrocyte member, and is expressed in the brain and pancreatic islets and localisted to the nuclear matrix, cytoplasmic vesicles and PML nuclear bodies. Beta4 spectrins are also essential for membrane stability and the molecular organization of the nodes of Ranvier .
Purification method: Protein G purified
Product type: Primary antibody
Antibody structure: Whole Antibody
Protein ID: NP_066022.2

Cláusula de descargo de responsabilidad

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Información de seguridad

• Código de clase de almacenamiento: 10 - Combustible liquids
• Clase de riesgo para el agua (WGK): WGK 2
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable