SAB4501074

Anti-GAD1 antibody produced in rabbit

affinity isolated antibody

• Sinónimos: 67 kDa glutamic acid decarboxylase, GAD-67, GAD1, Glutamate decarboxylase 1, Glutamate decarboxylase 67 kDa isoform
• UNSPSC Code: 12352203
• NACRES: NA.41

Propiedades

• biological source: rabbit
• Quality Level: 100
• conjugate: unconjugated
• antibody form: affinity isolated antibody
• antibody product type: primary antibodies
• clone: polyclonal
• form: buffered aqueous solution
• mol wt: antigen 66 kDa
• species reactivity: mouse, human, rat
• concentration: ~1 mg/mL
• technique(s): ELISA: 1:10000; immunohistochemistry: 1:50-1:100; western blot: 1:500-1:1000
• NCBI accession no.: Q99259
• UniProt accession no.: Q99259
• shipped in: wet ice
• storage temp.: −20°C
• target post-translational modification: unmodified
• Gene Information: human ... GAD1(2571)

Descripción

General description

Anti-GAD1 antibody detects endogenous levels of total GAD1 protein.

GAD1 gene (glutamate decarboxylase 1) codes for a glutamic acid decarboxylase enzyme (GAD67), that is of 67 kDa. It is mapped to human chromosome 2q31.1.

Immunogen

The antiserum was produced against synthesized peptide derived from human GAD1.

Immunogen Range: 471-520

Biochem/physiol Actions

GAD1 gene (glutamate decarboxylase 1) participates in GABA (γ-aminobutyric acid) synthesis. Variations in GAD1 results in hyperactivity in attention-deficit/hyperactivity disorder. It is also characterized with childhood-onset schizophrenia and cortical gray matter volume loss.

Features and Benefits

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Physical form

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Información de seguridad

• Storage Class: 10 - Combustible liquids
• wgk_germany: nwg
• flash_point_f: Not applicable
• flash_point_c: Not applicable