S7531
Anti-Staphylococcal α-Toxin antibody produced in rabbit
whole antiserum
Sinónimos:
Anti-α-Hemolysin
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About This Item
Productos recomendados
origen biológico
rabbit
Nivel de calidad
conjugado
unconjugated
forma del anticuerpo
whole antiserum
tipo de anticuerpo
primary antibodies
clon
polyclonal
mol peso
antigen 33 kDa
contiene
15 mM sodium azide
reactividad de especies
Staphylococcus aureus
envase
antibody small pack of 25 μL
técnicas
dot blot: 1:20,000
indirect ELISA: 1:50,000
Condiciones de envío
dry ice
temp. de almacenamiento
−20°C
modificación del objetivo postraduccional
unmodified
Categorías relacionadas
Descripción general
Staphylococcal α toxin, a water soluble 33kD single polypeptide, is a cytotoxic agent secreted by Staphylococcus aureus. This protein has membrane damaging properties and accounts for erythrocyte lysis. Hence it is also referred to as lethal hemolytic toxin or α-hemolysin . Anti-staphylococcal α-toxin antibody can be used for studies of the toxin-membrane interaction. Rabbit anti-staphylococcal α-toxin antibody reacts specifically with staphylococcal α-toxin but not with staphylococcal enterotoxin A, cholera toxin or pseudomonas exotoxin A.
Inmunógeno
α-toxin (α-hemolysin) from Staphylococcus aureus
Aplicación
Anti-staphylococcal α-toxin antibody can be used in indirect ELISA (1:50,000) and dot blot immunoassay (1: 20,000).
Applications in which this antibody has been used successfully, and the associated peer-reviewed papers, are given below.
Enzyme-linked immunosorbent assay (1 paper)
Enzyme-linked immunosorbent assay (1 paper)
Calidad
The antiserum has been treated to remove lipoproteins.
Cláusula de descargo de responsabilidad
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Código de clase de almacenamiento
10 - Combustible liquids
Clase de riesgo para el agua (WGK)
nwg
Punto de inflamabilidad (°F)
Not applicable
Punto de inflamabilidad (°C)
Not applicable
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Los clientes también vieron
María Belén Mestre et al.
Autophagy, 6(1), 110-125 (2010-01-30)
Staphylococcus aureus is a pathogen that causes serious infectious diseases eventually leading to septic and toxic shock. Classically S. aureus has been considered an extracellular pathogen, but cumulative evidence indicates that it invades cells and replicates intracellularly leading to staphylococcal
S Forti et al.
European journal of biochemistry, 181(3), 767-773 (1989-05-15)
alpha-Toxin, a lethal hemolytic toxin secreted by Staphylococcus aureus, forms ionic channels of large size in lipid membranes. To investigate the mechanism of channel assembly we have studied the kinetics of pore formation on small unilamellar vesicles. We have used
Alicia Lacoma et al.
Toxins, 13(2) (2021-02-11)
Staphylococcus aureus is a commensal and frequent colonizer of the upper respiratory tract. When mechanical ventilation disrupts natural defenses, S. aureus is frequently isolated from the lower airways, but distinguishing between colonization and infection is difficult. The objectives of this
Olivia A Todd et al.
mBio, 10(3) (2019-06-06)
Candida albicans and Staphylococcus aureus are among the most prevalent nosocomial pathogens that are responsible for severe morbidity and mortality, even with appropriate treatment. Using a murine model of polymicrobial intra-abdominal infection (IAI), we have previously shown that coinfection with
Shi-Jie Wan et al.
Frontiers in chemistry, 10, 877469-877469 (2022-04-19)
The emergence of antibiotic resistance in Staphylococcus aureus has necessitated the development of innovative anti-infective agents acting on novel targets. Alpha-hemolysin (Hla), a key virulence factor of S. aureus, is known to cause various cell damage and death. In this
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