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RAB1365

Sigma-Aldrich

Human CHL-1 ELISA

for serum, plasma and cell culture supernatants

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About This Item

UNSPSC Code:
41116158
NACRES:
NA.32

species reactivity

human

technique(s)

ELISA: suitable

input

sample type plasma
sample type cell culture supernatant(s)
sample type serum

assay range

inter-assay cv: <12%
intra-assay cv: <10%

shipped in

wet ice

storage temp.

−20°C

Gene Information

human ... CHL1(10752)

Categorías relacionadas

General description

CHL1 (cell adhesion molecule L1 like) gene codes for a cell-adhesion molecule. It belongs to the L1 family of cell adhesion molecules. The CHL1gene is mapped to human chromosome 3p26.
This ELISA antibody pair detects Human Cell Adhesion Molecule with Homology to L1CAM (L1CAM-2)

Application

For research use only. Not for use in diagnostic procedures.
Please refer to the attached Protocolfor details.

Biochem/physiol Actions

The axon guidance protein encoded by CHL1 (cell adhesion molecule L1 like) gene plays a major role in the guidance of thalamocortical axons and the multiplication and differentiation of neural progenitor cells. CHL1 acts as a tumor-suppressor gene in breast cancer (BC). Mutation in the axon guidance protein results in horizontal gaze palsy with progressive scoliosis (HGPPS). It participates in mental development.

Other Notes

A sample Certificate of Analysis is available for this product. Please type the word sample in the text box provided for lot number.

pictograms

Corrosion
GHS05

signalword

Warning

hcodes

H290

Hazard Classifications

Met. Corr. 1

Storage Class

8A - Combustible corrosive hazardous materials

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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Visite la Librería de documentos

Microarray based analysis of an inherited terminal 3p26.3 deletion, containing only the CHL1 gene, from a normal father to his two affected children
Cuoco C et al.
Orphanet Journal of Rare Diseases, 6(1), 12-12 (2011)
CHL1 hypermethylation as a potential biomarker of poor prognosis in breast cancer
Martin-Sanchez E, et al.
Oncotarget, 8(9), 15789-15789 (2017)
Lack of association between the CHL1 gene and adolescent idiopathic scoliosis susceptibility in Han Chinese: a case-control study
Qiu XS, et al.
BMC Musculoskelet. Disord., 15(1), 38-38 (2014)

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