P7412

Pirenzepine dihydrochloride

≥98% (TLC), powder

• Sinónimos: 5,11-Dihydro-11-[(4-methyl-1-piperazinyl)acetyl]-6H-pyrido[2,3-b][1,4]benzodiazepin-6-one dihydrochloride
• Fórmula empírica (notación de Hill): C₁₉H₂₁N₅O₂ · 2HCl
• Número de CAS: 29868-97-1
• Peso molecular: 424.32
• Número CE: 249-907-5
• Número MDL: MFCD00055214
• Código UNSPSC: 12352200
• ID de la sustancia en PubChem: 24277863
• NACRES: NA.77

Propiedades

• Nivel de calidad: 200
• Ensayo: ≥98% (TLC)
• Formulario: powder
• color: white to light yellow
• solubilidad: H₂O: 50 mg/mL
• cadena SMILES: Cl[H].Cl[H].CN1CCN(CC1)CC(=O)N2c3ccccc3C(=O)Nc4cccnc24
• InChI: 1S/C19H21N5O2.2ClH/c1-22-9-11-23(12-10-22)13-17(25)24-16-7-3-2-5-14(16)19(26)21-15-6-4-8-20-18(15)24;;/h2-8H,9-13H2,1H3,(H,21,26);2*1H
• Clave InChI: FFNMBRCFFADNAO-UHFFFAOYSA-N
• Información sobre el gen: human ... CHRM1(1128)

Descripción

Descripción general

Pirenzepine dihydrochloride is an anticholinergic agent. It is also considered as an antiulcer drug. It is used to treat myopia, gastric and duodenal ulcers. Pirenzepine dihydrochloride induces the dimerization of muscarinic M1 receptors.

Aplicación

Pirenzepine dihydrochloride has been used

• in transactivation of fibroblast growth factor receptor (FGFR).
• as a supplement in cell culture.
• for the stimulation of human fibroblasts

Acciones bioquímicas o fisiológicas

Selective M₁ muscarinic acetylcholine receptor antagonist.

Características y beneficios

This compound is a featured product for Neuroscience research. Click here to discover more featured Neuroscience products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

This compound is featured on the Acetylcholine Receptors (Muscarinic) page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Precaución

Hygroscopic; store desiccated at room temperature.

Información de seguridad

• Código de clase de almacenamiento: 11 - Combustible Solids
• Clase de riesgo para el agua (WGK): WGK 2
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable
• Equipo de protección personal: Eyeshields, Gloves, type N95 (US)